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Aging Clinical Trials

A listing of Aging medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 436 clinical trials
N Nadine J. McCleary, MD, MPH

Resilience and Equity in Aging, Cancer, and Health (REACH)

The purpose of this multi-phase research study is to understand how consultation of cancer care with a geriatrician can best improve outcomes for older adults with gastrointestinal malignancies.

70 years of age All Phase N/A
I Irene Matos, RN

Systems Investigation of Vaccine Responses in Aging and Frailty

This study will compare the immune response signatures (including immunologic, transcriptomic and metabolomic) of the two influenza vaccines approved for use in adults age 65 and over (Fluad and Fluzone High-Dose).

21 years of age All Phase 2
J Julie Schweiger

Dasatinib Plus Quercetin for Accelerated Aging in Mental Disorders

This pilot open-label study examines the effects of a combination of dasatinib plus quercetin two drugs that have known senolytics properties - on physiological aging in older individuals with depression or schizophrenia.

50 years of age All Phase 2
A Aprinda Indahlastari, PhD

Aging Intervention for MCI Population: The AIM Pilot Study

The current study is a mechanistic study to evaluate working memory gains from application of transcranial direct current stimulation (tDCS) in older adults with mild cognitive impairments (MCI) compared to cognitively healthy control

60 - 95 years of age All Phase N/A
L Lixia Yang, PhD

A Digital Active Aging Training Program for Older Adults

The proposed project aims to develop and validate a multi-dimensional digital active aging program integrated with resilience to promote the biopsychosocial functions of older adults aged 60, including Chinese older immigrants in Canada (Study 1) and English-speaking White Canadian older adults (Study 2). The proposed study takes a typical pretest-training-posttest …

65 years of age All Phase N/A
V Vishwadeep Ahluwalia, Ph.D.

Neurobiological Mechanisms of Aging and Stress on Prospective Navigation

Two hallmarks of both healthy aging and age-related disease are 1) memory and navigational deficits, particularly in orienting towards goal locations and planning how to navigate to them, and 2) increased susceptibility to stress and altered regulation of the stress response. However, there are marked individual differences in these age-related …

65 - 80 years of age All Phase N/A
S Sylvia Bähring, PD Dr.

VITAL: Vaccination, Immunity, Time-restricted Eating, Aging and Lifestyle

The aim of this study is to investigate the effects of a four-week time-restricted eating (TRE) intervention on autophagy, immune function, and vaccine response to a seasonal influenza and COVID-19 vaccines in older healthy subjects.

60 - 85 years of age All Phase N/A
N Nerea Becerra Tomás, PhD

Avocado Consumption and Cellular Aging in Breast Cancer Survivors

Women with breast cancer are at increased risk of comorbidities and premature mortality, potentially due to accelerated biological aging. Telomere attrition has been proposed as a biomarker of this process, which could be mitigated through interventions targeting behavioral factors such as diet. In recent years, avocado has drawn attention in …

40 - 65 years of age Female Phase N/A
S Sophia Liu Lab manager

Study of Healthy Aging and Physical Function With Elamipretide

This study will utilize a daily dose of elamipetide for 4 weeks and will screen a sufficient number of subjects for 30 subjects to enroll in the study. The planned duration of the study includes baseline measurement, followed by 4 weeks intervention period, a midpoint (2week ±3days) check-in phone interview, …

65 - 80 years of age All Phase 2

Pilot fMRI Studies of Aging-Related Effects of THC

The purpose of this study is to begin investigating acute impairment of various forms of memory and learning by Tetrahydrocannabinol (THC) in cannabis (CNB) compared to placebo, in a 2-session per subject double-blind, random assignment, placebo-controlled counterbalanced design in young to middle-aged adults.

18 - 75 years of age All Phase 2

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