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lung-disease Clinical Trials

A listing of lung-disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 3,282 clinical trials
A Alis Kostanoglu

The Effect of Gait Training Using Different Slope Types on Balance in COPD Patients

Although COPD is basically a respiratory system disease, its effects are not limited to the respiratory system. In this context, one parameter affected in COPD patients is balance. Recent studies have highlighted the importance of assessing balance and incorporating it into treatment options such as pulmonary rehabilitation. In this context, …

40 years of age All Phase N/A
D Damien JOLLY

Cohort for Research and Innovation in Chronic Inflammatory Respiratory Diseases

Chronic inflammatory pulmonary diseases including chronic obstructive pulmonary disease (COPD), interstitial lung diseases (ILD), bronchiectasis, and cystic fibrosis (CF) are characterized by lung inflammation and remodelling. Clinical, functional, microbiological, biological, pathological and prognosis features are highly variable and heterogeneous. A precise phenotyping is a key-element to better understanding the pathophysiology …

18 years of age All Phase N/A
C Carolin Steinack, MD

Noninvasive Early Detection of Lung Allograft Dysfunction After Lung Transplantation With Multiple Breath Washout Test

Chronic rejection, more commonly called bronchiolitis obliterans syndrome (BOS), is the leading cause of death beyond the first year post lung transplantation. The diagnosis of BOS is typically made by clinical, physiological, and radiographic parameters. Early detection would be desirable since it allows treatment modification to stop or delay the …

18 years of age All Phase N/A
X Xiaodong Xu

Tubeless Anesthesia in Preventing Lung Complications in Patients Undergoing Surgery for Early-Stage Lung Cancer

The study focuses on evaluating the effectiveness and safety of tubeless anesthesia in single-port thoracoscopic surgery for early-stage lung cancer patients. Traditional anesthesia methods risk postoperative complications like lung injury and respiratory issues. Tubeless anesthesia preserves spontaneous breathing without tracheal intubation, potentially reducing these complications and enhancing recovery. The study …

18 - 70 years of age All Phase N/A
S Szu-Yuan Wu, MD, PhD.

Oligo-Fucoidan Decrease Lung Radiation Damage

Fucoidan is FDA approved and in common use for treatment of angina. These studies will advance that work to human use. Successful mitigation of lung radiation damage and heart toxicity will improve the quality of life in veterans and non-veterans who are treated for lung cancer by radiation, and may …

20 - 90 years of age All Phase N/A
D Daniel Costa, MD, PhD

Osimertinib In EGFR Mutant Lung Cancer

This research study is studying a targeted therapy as a possible treatment for Non-Small Cell Lung Cancer (NSCLC) with an EGFR mutation. The names of the study drug involved in this study is: Osimertinib (Tagrisso)

18 years of age All Phase 2
L Ludovica Rizzo, Dr

Comparison of the Diagnostic Accuracy Between US-guided Percutaneous Lung Biopsies vs CT-guided in Peripheral Lung Lesions

A non-sponsored prospective randomized single-blind national multicenter interventional study which aims to compare the diagnostic accuracy between US-guided percutaneous lung needle biopsies and CT-guided in peripheral lung lesions. Secondary endpoints are: onset of number and type of complications during and after the procedure, within the first three hour; exposition to …

18 - 90 years of age All Phase N/A
F Finn Dittberner, MD

Prolonged Air Leakage After Major Lung Resection

The goal of this prospective randomized controlled trial is to investigate the clinical effects of autologous blood pleurodesis in the treatment of pulmonary air leaks on the first postoperative day following VATS pulmonary resections. Patients will through web-based randomization be randomly assigned into intrapleural instillation of autologous blood (intervention) or …

18 years of age All Phase N/A
H Huangxuan Zhao, PhD

DeepSparseCBCT for Low Dose Lung CBCT Reconstruction

The goal of this clinical trial is to learn if the DeepSparseCBCT model ensure high-quality CBCT image while reducing CBCT radiation dose. The main questions it aims to answer are: Can DeepSparseCBCT reduce CBCT radiation doses? Is the image quality of DeepSparseCBCT reconstruction consistent with that of existing clinical reconstruction …

18 years of age All Phase N/A
D Dong Wang, PH.D.

CIETAI and Sequential Radiotherapy in Squamous Lung Cancer

Central-type lung cancer refers to lung malignancies originating from the segmental bronchi and above. The most common tissue type is squamous cell carcinoma. Patients often present with cough, hemoptysis, hoarseness and also some critical conditions including superior vena caval obstruction syndrome. Therefore, effective treatment should be implemented as early as …

18 - 80 years of age All Phase 2

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