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lung-disease Clinical Trials

A listing of lung-disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 3,186 clinical trials
M Matty Mehrabi

M. Avium WGS During Mav-PD Treatment

This is a prospective observational study using whole genome sequencing (WGS) to investigate whether new strains (other than the initially identified strain(s)) of M. avium are responsible for persistently culture positive sputum during treatment (refractory disease), or the reversion to culture positive sputum after prior conversion to negative. The study …

18 years of age All Phase N/A

The Cardiac Stress and Electrocardiographic Changes Caused by Lung Cancer Surgery

Lung cancer surgery causes significant changes in the small circulation as well as changes in the intrathoracic anatomy. The effects of lung cancer surgery on electrocardiography and the cardiac stress associated with the procedures have not been previously extensively studied. The aim of the present study is to ascertain whether …

18 years of age All Phase N/A
S Su-Tso Yang, M.D.

TCM Constitution, Pattern Types, and Disease Factors in Primary Lung Cancer.

Recently, TCM has played an important role in adjuvant therapy for lung cancer. TCM treatment is based on pattern identification, and constitution theory is also used as a tool for TCM to predict the disease progression. Although there have been many researchs related to the pattern identification and constitution of …

18 - 100 years of age All Phase N/A
E Emilio Bria, Professor

Panomic Approach to Immune-Connected Assays in Small Cell Lung Cancer

The scope of the PICASSO project is to apply an innovative patient-based pan-omic approach to immune-assays, that will include multi-omics tumour characterization (genome, proteome, transcriptome), blood immune-cells and cytokine profiling, serological screening for paraneoplastic autoantibodies, clinical and metabolic measurements. The PICASSO project is aimed to validate in real world population …

18 years of age All Phase N/A
C Clare Dempsey

Developing Circulating and Imaging Biomarkers Towards Personalised Radiotherapy in Lung Cancer

In stage 3 NSCLC, treatment and follow-up are generally performed in a 'one-size-fits-all' manner. In the setting of metastatic lung cancer there has been considerable success identifying biomarkers, which allow treatments to be tailored and lead to more personalised medicine. In patients with stage 3 disease there exists a significant …

18 years of age All Phase N/A
G GEECHEN CHANG, MD, PhD

Development and Clinical Validation of Early-stage Lung Cancer Prognostic Kit

Lung cancer is the leading cause of cancer mortality worldwide in spite of the advanced progresses in medication and low-dose CT screening. The early-stage lung cancer accounts for less than 50% of newly diagnosed lung cancer in Taiwan, even in stage IB patients proximately 30% still suffer from recurrence and …

20 years of age All Phase N/A
T Timothy Sheehan

Piloting a Virtual Navigation (VN) System for Bronchoscopic Lung Nodule Sampling

The overall goal is to evaluate the role of a Virtual Navigation (VN) system (the Virtual Navigator) in the bronchoscopic evaluation and tissue sampling of lung cancer and other chest lesions at the Penn State Hershey Medical Center (HMC). The Virtual Navigator is a software package that runs on a …

18 years of age All Phase N/A
R Richard T Meehan, MD

Lung Clearance Index to Identify Scleroderma Patients at Risk for ILD

This National Jewish Health (NJH) Investigator Initiated pilot study funded by the Shah Foundation will prospectively perform a non invasive lung function test called Lung Clearance Index (LCI) to determine if 50 scleroderma patients without evidence of lung disease who have evidence of small airway inflammation or impairment to airflow …

21 - 75 years of age All Phase N/A
J Jenna Wong, MSc

Diaphragm Structure and Pathobiology in Patients Being Bridged to Lung Transplant

This study is designed to characterize the changes in diaphragm structure, function and biology during bridging to lung transplant by mechanical ventilation or extracorporeal life support.

18 years of age All Phase N/A
C Chris Roberts

A Study of Post COVID-19 Mechanisms for Chronic Lung Sequelae

The purpose of this study is to understand why some people experience long term effects, such as shortness of breath and fatigue, after a severe COVID-19 infection

18 years of age All Phase N/A

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