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Kidney Stones Clinical Trials

A listing of Kidney Stones medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 88 clinical trials
D Daniel Fuster, MD

Indapamide and Chlorthalidone to Reduce Urine Supersaturation for Kidney Stone Prevention

The aim of this study is to test the efficacy of the two long-acting thiazide-like diuretics indapamide and chlorthalidone in reducing urine supersaturation for calcium oxalate and calcium phosphate compared to the short-acting thiazide diuretic hydrochlorothiazide for the prevention of calcium-containing kidney stones.

18 years of age All Phase 2
M Megan Prochaska, MD

SGLT2i in Kidney Stones

This study is looking at whether empagliflozin, a medication typically used for diabetes and heart conditions, may affect factors that contribute to kidney stone formation. The research focuses on people who have had calcium-based kidney stones, i.e. calcium oxalate or calcium phosphate stones. Previous studies in those without kidney stones …

18 - 70 years of age All Phase 0
s safaa abdelmoez elnaggar, professor

Outcomes of Using FANS With FURS in TTT of Lower Calyceal Stones.

The aim of this study is to evaluate and assess the outcomes of flexible ureteroscopy (FURS) with flexible and navigable suction UAS (FANS) in the treatment of lower calyceal stones.

18 years of age All Phase N/A
W Wei Zhu, M.D.

FANS-Assisted Mini-PCNL for Complex Renal Stones

This prospective pilot study aims to evaluate the feasibility, safety, and preliminary clinical outcomes of a novel mini-percutaneous nephrolithotomy (mini-PCNL) technique integrating a flexible mini-nephroscope with a flexible and navigable suction access sheath (FANS) for the treatment of complex renal stones. Thirty consecutive patients with renal stones ≥2 cm will …

18 - 75 years of age All Phase N/A
L Li Peng

Research on Early Warning and Diagnosis & Treatment Pathway for Micro Kidney Stones

Exploring abnormal metabolism in kidney stone patients and developing drugs for kidney stone treatment and their mechanisms of action.

18 - 70 years of age All Phase N/A
K Karim BENSALAH

Impact of Forced Diuresis on the Residual Fragment Rate After Flexible Ureteroscopy for Destruction of Kidney Stones With Laser

In view of the positive results of the numerous studies conducted on forced diuresis after extra-corporeal lithotripsy, the investigators chose to evaluate forced diuresis by injection of Furosemide associated with intravenous hydration, which has never before been the subject of a specific analysis.

18 - 80 years of age All Phase 3
N Naeem Bhojani, MD

Thulium Fiber Laser Prospective Trial

This is a multi-center, prospective clinical trial to assess the effect of TFL for the lithotripsy of kidney stones.

18 years of age All Phase N/A
S Shalyn Littlefield, MSc

Thulium Fiber Laser (TFL) Versus Holmium MOSES Laser for Ureteroscopic Management of Kidney Stones

This study aims to compare the efficacy and safety of both types of lasers, Holmium MOSES and TFL, in management of kidney stones requiring treatment.

18 years of age All Phase N/A
M Mantu Gupta, MD

CaOx Stone Prevention

This single-center randomized controlled trial at Mount Sinai West will enroll 80 patients undergoing percutaneous nephrolithotomy for calcium oxalate stones. Participants will be randomized to receive either empiric therapy or selective therapy guided by 24-hour urine evaluation. The primary outcome is change in calcium oxalate supersaturation at 4 weeks, aiming …

18 years of age All Phase 4
M Mingyong Li, MD.

Percutaneous Nephrolithotomy Without a Ureteral Catheter

Conventional Percutaneous nephrolithotomy (PCNL) surgery requires the patient to first undergo retrograde transurethral ureteroscopic insertion of the ureteral catheter in the lithotomy position, and then change the patient to the prone position. However, repeated operation on the ureter can bring about immediate and long-term negative effects, such as ureteral false …

18 - 80 years of age All Phase N/A

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