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Sleep Disorders Clinical Trials

A listing of Sleep Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 168 clinical trials
J Jeff S Volek, PhD

Ketone Conferred Resiliency Against Sleep Restriction With Nutritional Intervention.

Sleep deprivation is a major problem in military populations. Some major consequences of sleep loss are inability to concentrate, poor work efficiency, and increase in errors during daily tasks. Ketogenic supplementation is speculated to alleviate some sleep deprivation issues via action of ketones. Ketones are small molecules that appear in …

18 - 40 years of age All Phase N/A
W William D Killgore, PhD

Caffeine Optimization Versus Standard Caffeine Dosage (2B-2)

This clinical trial will be a comparison between personalized recommended caffeine dosing regimen versus the standard recommended caffeine dosing regimen for sustaining performance during sleep deprivation and minimizing side effects and subsequent sleep disruption. The questions this study aims to answer are: Whether the personalized caffeine recommendations improve vigilance, sleepiness, …

18 - 39 years of age All Phase N/A

Exogenous Melatonin in Intensive Care Unit Chronodisruption

To this day, a small number of studies have evaluated the effect of melatonin on the modifications of the characteristics of sleep in critical care units, with mostly a small studied population. However, no study has been realized on a large population, nor has it evaluated the association between genetic …

18 years of age All Phase 3
J Janet Mullington, PhD

The Effect of Sleep Loss on Emotion Regulation

The study is designed to investigate the impact of three nights of sleep restricted to 4 hours per night, on the processing and regulation of emotional information compared to Insomnia Disorder and control. The investigators will address and attempt to answer two questions. (i) How do three nights of reduced …

18 - 40 years of age All Phase N/A
B Balachundar Subramaniam, MD, MPH

Resilience to Sleep Deprivation and Changes in Sleep Architecture in Shoonya Meditators

This study aims to investigate the effect of a 15-minute meditation practice on sleep architecture and high-frequency Heart Rate Variability (HF-HRV), as well as cognitive performance after both a well-rested and sleep-deprived night.

18 - 60 years of age All Phase N/A
M Minna Kuurne-Koivisto

Tailored Treatment of Insomnia in Social and Health Care Sector Shift Workers in Occupational Health Care

The goal of this clinical trial is to evaluate the usefulness of cognitive behavioural therapy for insomnia (CBT-I) tailored to shift workers in the social and health care sector. The study will also learn about the shift workers' experiences of the acceptability and feasibility of CBT-I and investigate which features …

18 - 65 years of age All Phase N/A

Reestablishing Sleep and Circadian Alignment in Medical Intensive Care Unit (MICU) Patients Via a Mechanistic RCT of an Sleep Chronobundle

More than 5 million patients are admitted to the intensive care unit every year in the United States; most of these patients experience profound sleep and circadian disruption. Promotion of circadian alignment (i.e., alignment of the body's clocks) would make it possible to strategically schedule behaviors such as sleep and …

18 years of age All Phase N/A
R Ronette Blake, MS

Experimental Manipulation of Sleep and Circadian Rhythms and the Role Played on Reward Function in Teens

Adolescence is a time of heightened reward sensitivity and greater impulsivity. On top of this, many teenagers experience chronic sleep deprivation and misalignment of their circadian rhythms due to biological shifts in their sleep/wake patterns paired with early school start times. Many studies find that this increases the risk for …

13 - 15 years of age All Phase N/A
S Study Team

Lemborexant in Delayed Sleep Phase Syndrome

The purpose of the study is to evaluate whether Lemborexant is more effective than placebo in shortening sleep onset latency in patients with delayed sleep phase syndrome (both type 1 and type 2). This will be tracked using sleep logs as well as actigraphy. In this 2-year study, we will …

18 years of age All Phase 4
J Jessee Dietch, PhD

Shift Worker Intervention for Sleep Health

The aim of this study is to pilot test a comprehensive, personalized, media-augmented telehealth intervention ("SWISH") designed to improve sleep health among shift workers.

18 - 65 years of age All Phase N/A

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