Advanced Filters
noise

dupuytrens-disease Clinical Trials

A listing of dupuytrens-disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 8 clinical trials
E Elias Sawaya, MD

Efficacy of Aponeurectomy on the 2-year Recurrence Rate of Dupuytren's Disease

Dupuytren's disease is a frequent hereditary disease in Northern Europe. It is a degenerative disease affecting the palmar aponeurosis of the hand. It develops a progressive contractile fibrosis which cuts the hypodermic fatty tissue, adheres to the skin and the phalanges, gradually bending the affected rays, resulting in significant functional …

18 - 100 years of age Both Phase N/A
L Lore Hermans, MSc

Palmaris Longus Muscle and Dupuytren

Dupuytren disease is a medical condition characterized by the painless formation of nodules in the palm of the hand. Cords are formed on the palmar fascia, a connective tissue sheet in the palm of the hand. This fascia is seen as the vestigial remnant of the palmaris longus tendon. The …

50 - 100 years of age Both Phase N/A
D Daniel Muder, MD

Effectiveness of Night Splinting After Percutaneous Needle Fasciotomy in Dupuytren's Contracture

Dupuytren's contracture (DC) is associated with progressive finger flexion and extension deficit caused by fibrosis in the palm and digits. Treatment options include minimally invasive procedures such as percutaneous needle fasciotomy (PNF) and collagenase clostridium histolyticum injections as well as open fasciectomy. PNF has recently become more popular in Sweden …

18 - 100 years of age Both Phase N/A

The Effects of Prophylactic Limited Palmar Fasciectomy on Surgical Outcomes and Scarring

Research is instrumental for improving medical care and the patient experience. Finding new surgical techniques can create better outcomes and minimize recovery time and complications for patients. Some patients undergoing trigger finger surgery with a pre-existing Dupuytren's cord may develop a thickened surgical scar after surgery, which can cause discomfort, …

18 - 100 years of age Both Phase N/A
L Laura H Matthiesen, PhD Student

Percutaneous Needle Fasciotomy +/- Corticosteroid Injection for Dupuytren's Contracture

Comparing percutaneous needle fasciotomy +/- corticosteroid injection for Dupuytren's contracture affecting metacarpophalangeal joints. A clinician-initiated, multicenter, randomized controlled trial.

45 - 99 years of age Both Phase 4
J Johann BEAUDREUIL, PUPH

Effectiveness of Percutaneous Needle Aponeurotomy

The main objective is to investigate if percutaneous needle aponeurotomy is non-inferior to open surgery using aponeurectomy in treatment of flexion contracture due to Dupuytren's disease. Our hypothesis is that percutaneous needle aponeurotomy has suitable efficacy and safety profile for large application in the treatment of Dupuytren's disease and that …

18 - 100 years of age Both Phase N/A
L Lore Hermans, MSc

Micronerves in Dupuytren and the Impact of Its Dissection on Recurrence

Dupuytren disease (DD) is a highly prevalent disabling hand disease. Spontaneous fibrosis nodules and strands in the palms of the hand cause finger contractures in disturbing positions and movement restrictions. Finger movement can be restored by surgery (removing the fibrosis tissue), but recurrence is a major problem and this is …

18 - 100 years of age Both Phase N/A
L Lore Hermans, MSc

Goniometry and Goniometric Measurement on Standardised Images in Dupuytren's Disease

Measuring range of motion (ROM) is essential in detecting musculoskeletal deficits, monitoring the effects of treatment and progression of the disease. In Dupuytren's disease the active and passive extension deficits (AED, PED) of digits 4 and 5 are usually clinically measured using a universal, short arm goniometer which is considered …

18 - 100 years of age Both Phase N/A

Rewrite in simple language using AI