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Pneumonia Clinical Trials

A listing of Pneumonia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 271 clinical trials
S Sara Ardren, PA

Neuromuscular Electrical Stimulation in COPD/Community Acquired Pneumonia

In older adults hospitalized for acute medical conditions, immobility, clinical treatments, and the illness itself contribute to physical deconditioning and delirium, hospital-acquired impairments that increase risk for long-term physical and mental disability, other morbidities, and death. In patients with acute respiratory failure, hospital-acquired functional impairments persist long after hospitalization, due …

50 years of age All Phase N/A

Rezafungin for Treatment of Pneumocystis Pneumonia in HIV Adults

This study aims to generate clinical data on the efficacy, safety, and tolerability of rezafungin combined with 7 days of co-trimoxazole for treatment of Pneumocystis pneumonia (PCP) in adults living with human immunodeficiency virus (HIV), which would expand the knowledge of clinical use of rezafungin.

18 years of age All Phase 2
A Antoine GOURY

Ventilator Associated Pneumonia Multiplex PCR for Anti-Infective Regimens

Ventilator-associated pneumonia (VAP) remains one of the main nosocomial infections acquired in the intensive care unit (ICU). VAP is pneumonia occurring 48 hours after intubation. Today, bronchoalveolar lavage (BAL) is used for microbiological diagnosis, with bacterial culture and antibiotic susceptibility results within 48 to 72 hours. Multiplex PCR can detect …

18 years of age All Phase N/A
A Abdallah soudi

Aspiration Pneumonia in Cerebrovascular Stroke Patients Suffering From Bulbar Palsy

One of the most serious complications in the critically ill patient complaining of bulbar palsy is aspiration pneumonia. These patients are scheduled for nasogastric tube feeding trying to avoid recurrent aspiration and subsequent aspiration pneumonia. Even though, the risk of aspiration is still present. Putting a total parenteral nutrition regimen …

18 years of age All Phase 4
L Loma Linda University Health

The Effects of Endotracheal Suctioning on Pain and Serum Markers

The goal of this experimental study is to understand if endotracheal tube (ETT) suctioning increases pain and causes stress on the body in intubated adult ICU patients. These patients are already on ventilators, which means they need suctioning to keep their airways clear, but this procedure may be uncomfortable and …

18 years of age All Phase N/A
J Jeffrey Pernica, MD

Optimizing Care for Children Hospitalized With Community-acquired Pneumonia: Novel Diagnostics

Children are commonly hospitalized because of community-acquired pneumonia. Despite the fact that many of these children have viral disease, a majority is treated with antibiotics. These antibiotics will not accelerate recovery in those with viral pneumonia and can cause harm. We are interested in exploring whether the MeMed BV - …

6 - 18 years of age All Phase N/A

High-dose Inhalations of Nitric Oxide in the Treatment of Pneumonia

This is a multicenter, prospective randomized controlled trial. At least 2 but no more than 5 centers are expected to participate in the study. The primary objective is to test the hypothesis that the addition of high-dose inhaled nitric oxide therapy to standard treatment has a positive effect on the …

18 years of age All Phase N/A
M Mian Muhammad hassan Ahmed DR. Hassan, Post Graduate Resident

The Role of Melatonin as an Adjuvant Therapy in Childhood Pneumonia

The goal of this study is to compare the mean length of hospital stay between children with pneumonia receiving melatonin as an adjuvant therapy and those receiving standard of care alone. The hypothesis is that combining oral melatonin with standard treatment can reduce the length of hospital stay as compared …

1 - 12 years of age All Phase 1/2
J Jeffrey Pernica, MD

Optimizing Care for Children Hospitalized With Community-acquired Pneumonia: Short-course Therapy

Children are commonly hospitalized because of community-acquired pneumonia (CAP). There are multiple high-quality randomized trials of short-course antibiotic therapy (3-5 days of treatment) for adults hospitalized with CAP - but there is very little evidence in children. We intend to do a pilot RCT of short-course (3-5 days) vs standard-duration …

6 - 18 years of age All Phase 4
M Maiada MD Kamaleldin Hashem, Ass. Prof.

Role of Oral Care in Prevention of Nosocomial Pneumonia Among COPD Patients

Poor dental hygiene has been linked to respiratory pathogen colonization in ICU patients. Therefore, respiratory pathogens tend to colonize dental plaque and oral mucosa in these populations. Therefore, strategies to eliminate respiratory pathogens from the oral cavity may improve oral hygiene and decrease the development of nosocomial pneumonia.

18 years of age All Phase N/A

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