Advanced Filters
noise

fever Clinical Trials

A listing of fever medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 159 clinical trials
O Olivia Randazza, PharmD

Antimicrobial Revision in Persistent Febrile Neutropenia

Febrile neutropenia is often seen in patients with hematologic malignancies who receive cytotoxic chemotherapy. These patients are usually placed on posaconazole prophylaxis upon starting chemotherapy. If an episode of febrile neutropenia occurs, generally an anti-pseudomonal beta lactam, like cefepime or piperacillin-tazobactam, is initiated. In patients who continue to fever on …

18 - 100 years of age Both Phase 4
B Barbara Gehler, MD, Dr.

Hyperthermia with Chemoradiotherapy in Rectal Cancer

The goal of this clinical trial is to evaluate the efficacy of deep regional hyperthermia in the context of radiochemotherapy followed by consolidation chemotherapy in locally advanced rectal cancer. Questions it aims to answer are: Can surgery be avoided if the tumor completely regresses? How high is the Local re-growth …

18 - 100 years of age Both Phase N/A
L Lana Ghanipour

Efficacy of Hyperthermic Intraperitoneal Chemotherapy

A dose titration study and a combined superiority registry-based open-label randomized control trial is planned to answer the trial objectives. The study will be registry-based to allow simpler and more comprehensive follow-up. Patients with colorectal cancer will be treated with cytoreductive surgery (CRS) together with either standard oxaliplatin HIPEC (the …

18 - 74 years of age Both Phase 3
M Marianne ROUMY

Clusterin, Ptx3 and Pediatric Febrile Neutropenia (CluPPFeN)

Febrile aplasia is a common occurrence in children/adults treated with chemotherapy for malignant blood diseases or solid cancers. This acquired deficiency of immunity mainly causes susceptibility to bacterial and fungal infections, pathogens normally recognized by specific receptors of innate immunity (Pattern Recognition Receptor, PRR). Thus, the febrile episodes in the …

- 18 years of age Both Phase N/A
M Ming-Yuan Chen, MD, PhD

Plasma Radiofrequency Ablation at Low Temperature Versus Electrocautery Block Resection at High Frequency for Localized Recurrent Nasopharyngeal Carcinoma

This study aims at exploring whether plasma radiofrequency ablation at low temperature is associated with better survival outcome in localized recurrent nasopharyngeal carcinoma by conducting a randomized controlled trial of plasma radiofrequency ablation at low temperature versus electrocautery block resection at high frequency for localized recurrent nasopharyngeal carcinoma. If the …

18 - 70 years of age Both Phase N/A
M Mazdak Momeni, MD

Hyperthermic Intraperitoneal Chemotherapy for Recurrent Ovarian Cancer

This is a phase I prospective study with the primary objective to compare the efficacy and safety of Surgical cytoreduction (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in treatment of recurrent ovarian, primary peritoneal or fallopian tube cancers. Eligible patients consenting to this protocol will undergo their scheduled surgical procedure. After …

21 - 100 years of age Both Phase 1
T Teresa Bernal del Castillo, MD PHD

A Trial of Fosfomycin vs Ciprofloxacin for Febrile Neutropenia

Randomized phase 3 trial to compare efficacy and safety of oral fosfomycin versus ciprofloxacin to prevent febrile neutropenia in patients with acute leukemia or recipients of hematopoietic stem cell transplant.

18 - 100 years of age Both Phase 3
M Marc Peeters, Professor

Safety Study of Whole Body Hyperthermia for Advanced Cancer

Millions of patients die of cancer every year. There are several methods to treat cancer, including surgery, chemotherapy, radiotherapy and immunotherapy. Recently, hyperthermia therapy started playing a role in cancer therapy. It has shown effect in animal experiments and clinical practice. The sponsor has developed a novel device to use …

18 - 75 years of age Both Phase N/A

Human Immune Responses to Yellow Fever Vaccination

The goal of this study is to use the live attenuated Yellow Fever Vaccine as a safe and effective model for viral infection to understand human immune response to viral antigens. Study participants will receive the yellow fever vaccine and participation in the study may be as short as one …

18 - 45 years of age Both Phase 4
D David Peprah

Transnasal Induction of Normothermia for Neurogenic Fever

The objective of this study is to evaluate the efficacy of the COOLSTAT® Transnasal Thermal Regulating Device in reducing temperature in a population of febrile subjects who meet the inclusion/exclusion criteria.

18 - 85 years of age Both Phase N/A

Rewrite in simple language using AI