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fever Clinical Trials

A listing of fever medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 150 clinical trials

DIStinguishing ChildrEn at Low Risk of Severe infectioN in Case of Febrile Neutropenia-7: Impact Study of a Clinical Decision Rule

Febrile neutropenia (NF) is the leading cause of unscheduled hospitalization in children with cancer. Management classically involves emergency admission to hospital for intravenous antibiotic treatment until resolution of fever and neutropenia. However, children with NF are a heterogeneous group with varying risks of severe infection (10-29%). This approach, which is …

1 - 18 years of age Both Phase N/A
A Abdulwasiu Bolaji Tiamiyu

A Lassa Fever Vaccine Trial in Adults and Children Residing in West Africa

A Phase 2 Randomized, Double-Blinded, Placebo-Controlled Clinical Trial to Evaluate the Safety, Tolerability, and Immunogenicity of rVSV∆G-LASV-GPC Vaccine in Adults and Children Residing in West Africa

18 - 70 years of age Both Phase 2
J Javier Redondo-Calvo, MD,PhD

Intrabdominal Hyperthermic Chemotherapy and Pancreatic Cancer

A randomized, multidisciplinary study, Phase II-III clinical trial.The study is opened to the incorporation of other centers that would increase the power of the obtained results . Our hypothesis considers that using Hyperthermic Intra-abdominal Chemotherapy,HIPEC, with gemcitabine after cytoreductive surgery ,will decrease tumor progression of pancreatic cancer by reducing the …

18 - 100 years of age Both Phase 2/3
V Vratislav Strnad, MD

Salvage Brachytherapy and Hyperthermia for Recurrent H&N-tumours

The aim of the present trial is to assess the prospective results of protocol-based interstitial pulsed-dose-rate (PDR) brachytherapy with interstitial hyperthermia (iHT) in a group of selected patients where salvage surgery with clear resection margins was not possible.

18 - 100 years of age Both Phase N/A

Potential of Moderate Whole Body Hyperthermia to Enhance Response

Using moderate whole-body hyperthermia (mWBH) in tumor patients to see the influence on circulating tumor cells, tumor response, quality of life, fatigue, psyche, immune response and tumor microenvironment

18 - 100 years of age Both Phase 2
A Attila M Szasz, M.D./Ph.D.

Neoadjuvant Concomitant Modulated Electro-hyperthermia in HER2-negative Breast Cancer

The aim of this study is to investigate whether the application of concomitant modulated electro-hyperthermia in a neoadjuvant chemotherapeutic setting is beneficial for patients with HER2-negative, stage II-III breast cancer.

18 - 100 years of age Female Phase 2/3
Y Yuri Vanbiervliet, MD

Stopping Antibiotics After 3 Days for the Treatment of High-risk FEbrile Neutropenia

The goal of this clinical trial is to compare a short course of antibiotics in patients in whom no bacterial infection is found with the current "golden standard": long-term antibiotic treatment in adult hematology patients who develop neutropenic fever. The main question it aims to answer is: whether the short-term …

16 - 100 years of age Both Phase 4

Study of DPPG2-TSL-DOX Combined With Hyperthermia in Soft Tissue Sarcoma

This study aims to explore a new therapeutic approach for advanced soft tissue sarcoma (STS) by investigating the safety, tolerability, and maximum tolerable dose (MTD) of DPPG2-TSL-DOX combined with regional hyperthermia (RHT) in patients who have been pre-treated with doxorubicin (DOX).

18 - 100 years of age Both Phase 1
D Dario Baratti, MD

Patient-tailored Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for Colorectal Peritoneal Metastases (OrganoHIPEC)

The objective of this clinical trial is to demonstrate that cytoreductive surgery and patient-tailored hyperthermic intra-peritoneal chemotherapy (HIPEC) will increase efficacy in controlling peritoneal disease. Tridimensional cell cultures (organoids) derived from colorectal cancer peritoneal metastases are used to select the most active drugs in an in vitro HIPEC model on …

18 - 75 years of age Both Phase N/A
J Jeannine M Haller, RN, CCRP

Phase 2 Safety and Immunogenicity Study of Rift Valley Fever Vaccine

This study is to collect safety and immunogenicity data for an Rift Valley Fever (RVF) vaccine

18 - 65 years of age Both Phase 2

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