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constipation Clinical Trials

A listing of constipation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 67 clinical trials
A Aysenur Aydogan, Bachelor

Technology-based Constipation Prevention Training

The aim of this study is to determine the effect of technology-assisted constipation prevention training on the management of constipation in hospitalised orthopaedic patients. This is a quasi-experimental study. The population of the study will consist of patients admitted to the Orthopaedic Clinic of Burdur State Hospital between January 2024 …

18 - 100 years of age Both Phase N/A
F Faming Zhang, MD, PhD

Washed Microbiota Transplantation for Chronic Constipation in Adults

This is a single-center, randomized, double-blind, placebo-controlled, dose-exploring clinical study to explore the safety and efficacy of washed microbiota transplantation (WMT) for patients with chronic constipation.

18 - 70 years of age Both Phase 1/2
K Kelly J Feuerhak

Use of a Squatting Assist Device in Patients With Constipation

Constipation is a very common problem. Western style toilets that are nearly universal in the United States require the person to sit on the toilet. However, results from uncontrolled studies suggests that a squatting posture (as prevalent in many foreign countries) may be better at facilitating evacuation compared to a …

18 - 80 years of age Female Phase 2
K Kelly J Feuerhak

Understanding Mechanisms of Normal and Disordered Defecation

Researchers are trying to better understand why constipation occurs and improve the tests for diagnosing these conditions.

18 - 80 years of age Both Phase N/A
D Dianne Glass, MD, PhD

Bowel Function After Minimally Invasive Hysterectomy

Postoperative constipation affects up to a third of women undergoing minimally invasive (MIS) gynecologic surgery and is a major source of anxiety and discomfort. The average time to first bowel movement after gynecologic surgery is about 2 to 4 days and some factors responsible for this include anesthesia inhibitory effect …

18 - 100 years of age Female Phase 4
Z Zhi Li, MD PhD

Comparison of Circular(Soave) and Heart-shaped Anastomosis in Hirschsprung's Disease: A Prospective Multicenter Randomized Controlled Trial

Comparison of Circular(Soave)and Heart-shaped Anastomosis in Hirschsprung's disease.

- 14 years of age Both Phase N/A
E Erik Andrewski, MD

Evaluation of Fecal Microbiome Changes After Antegrade Continence Enema Placement and Initiation of Bowel Flush Regimen

This study will evaluate changes in the fecal microbiome in constipated pediatric patients before and after antegrade continence enema placement and initiation of antegrade enema flushes. Subjects will have their microbiome sequenced prior to placement by obtaining a fecal sample. Pre-antegrade continence enema placement results will be compared to fecal …

2 - 21 years of age Both Phase 4

The Effect of Naldemedine on Opioid-induced Bowel Dysfunction

Opioid-induced bowel dysfunction is a frequent condition during opioid therapy for chronic pain. Indeed, up to 90% of people on opioid treated patients experience constipation. Standard laxative treatment is often ineffective in opioid-induced constipation, but peripheral acting mu-receptor antagonists (PAMORAs) have the potential to block the effects of opioids in …

20 - 40 years of age Male Phase 2

Effect of Abdominal Massage Versus Visceral Manipulation on Constipation

The study compares the effect of abdominal massage vs. visceral manipulation on constipation status and quality of life in adults. Chronic idiopathic constipation (CIC) is considered a common functional bowel disorder characterized by difficult, infrequent, and/or incomplete defecation. It has a great impact on the quality of life and on …

20 - 40 years of age Both Phase N/A
G Giovanni Cammarota

Fecal Microbiota Transplantation to Relieve Symptoms of Irritable Bowel Syndrome With Constipation

Irritable bowel syndrome (IBS) is a complex multifactorial functional disorder, whose pathophysiology is largely associated to an impairment of the intestinal microbiota composition, namely dysbiosis. Thus, the modulation of the gut microbiota has been proposed as a possible therapeutic strategy for IBS patients alongside with current available drugs. Fecal microbiota …

18 - 100 years of age Both Phase N/A

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