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Congestive Heart Failure Clinical Trials

A listing of Congestive Heart Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 793 clinical trials
M Marco Montomoli

Effect of the Use of Dapagliflozin in Patients With Refractory Heart Failure

Cross-over, 2-sequence, 2-treatment, 2-period single-centre, phase IV, randomized, open label study.

18 years of age All Phase 4

Nurse-led Education on Patients With Chronic Heart Failure and Their Informal Caregivers

The current study intends to examine the influence of nurse-led education on patients with chronic heart failure and their caregivers, with the goal of optimizing care for both and improving patients' clinical outcomes.

18 years of age All Phase N/A

Inspiratory Muscle Training in HFpEF

This study is being done to determine how inspiratory muscle training impacts inspiratory muscle function during exercise in heart failure patients.

18 years of age All Phase N/A
J Jason Ortman

Brain Volume and Cardiac Function in Heart Failure

Patients with heart failure (HF) exhibit greater structural brain alterations and higher dementia risks than the general population. Neural atrophy in nearly every region of medical limbic circuit has been observed in HF patients. Reduction of cerebral blood flow has been suggested as the pathophysiological pathway linking HF and structural …

21 years of age All Phase N/A
D Diana A Gorog

Safety of AI-Powered Virtual Assistant in Outpatient Management of Heart Failure

The aim of this pilot randomized study is to examine whether integrating the SIRIO-HF virtual assistant (VA) into the outpatient management of participants recently discharged from hospital with a new diagnosis of heart failure (HF), may reduce the need for regular medical assessment and the healthcare burden, reduce variability in …

18 years of age All Phase N/A
A Almagul Kushugulova

The Gut Microbiome in Chronic Heart Failure

there are numerous studies, most of which are predominantly associative in nature, investigating the association between the gut microbiota and various pathologies. However, to establish a causal relationship between microbiome composition and chronic heart failure (HF), clinical studies are needed, particularly using probiotics that can modify the composition and function …

18 years of age All Phase N/A
L Li Xuping, PhD

Comparison of Catheter Plus Marshall Vein Ablation vs. Catheter Ablation Alone in Persistent AF With Heart Failure

This multicenter, randomized controlled trial aims to compare the clinical efficacy and safety of combining catheter ablation with Marshall vein ethanol ablation versus catheter ablation alone in patients with persistent atrial fibrillation (AF) and concomitant heart failure. Persistent AF is a common arrhythmia that significantly impacts the quality of life …

18 - 80 years of age All Phase N/A
S Sabina Frljak, MD, PhD

Cardiovascular Genistein Therapy for Heart Failure Inflammation

This Phase 1b/2a open-label study is designed to assess the safety and efficacy of genistein in patients with heart failure (HF). The investigation will focus on its impact on inflammatory and cardiometabolic biomarkers, as well as its effects on cardiac function and exercise capacity. Blood samples will be collected at …

40 - 80 years of age All Phase 1/2
K Keren Recanati

Assessment of Safety and Accuracy of the Microtech System in Patients Undergoing Left Ventricular Assist Device Implantation

The Microtech-LVAD study is designed as a prospective, single arm, multi-center early feasibility study. Approximately 15 patients will be enrolled in the study. The study will be limited to patients in whom it is decided, based on routine clinical practice, that the LVAD will be implanted via a midline sternotomy. …

years of age All Phase N/A
M Mia Levanto

Identifying Markers of Exercise Training in Heart Failure

The heart failure syndrome that occurs when the heart is too sick to properly do its job. One of the main symptoms is difficulty with exercise. One way to improve symptoms is to start patients in a 12 week exercise program called cardiac rehabilitation. Cardiac rehabilitation been shown to improve …

18 - 89 years of age All Phase N/A

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