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Asthma Clinical Trials

A listing of Asthma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 347 clinical trials
P Peter J Niedbalski, PhD

Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease

The purpose of this study is to develop and evaluate the usefulness of hyperpolarized (HP) 129Xe gas MRI for regional assessment of pulmonary function.

3 years of age All Phase 1

C-mo System 1.0's Validation - Cough Monitoring

Cough is one of the most reported symptoms, especially associated with respiratory diseases. Additionally, cough contains extremely insightful information regarding the patient's health. It is a symptom full of physiopathological information, which can be extremely helpful in clinical practice. However, cough is not currently used as a clinical biomarker given …

2 years of age All Phase N/A
L Lieve van Brakel, MSc

Plant Stanol Esters and Preventing Asthma Symptoms

Plant stanols are known to lower low-density lipoprotein cholesterol. However, studies have suggested that these compounds also influence the immune system. Asthmatic responses are predominantly T helper (Th)2 cell dependent, while plant stanols were previously found to activate Th1 cells and shift the immune response away from the Th2 cell …

18 - 70 years of age All Phase N/A
S Sarah Svenningsen, PhD

Exploring the Utility of Hyperpolarized 129Xe MRI in Healthy Volunteers and Patients With Lung Disease

This is a single centre exploratory study that aims to apply hyperpolarized xenon-129 (129Xe) magnetic resonance imaging (MRI) methods and measurements in individual patients with and without lung disease to better understand lung structure and function and evaluate response to therapy delivered as a part of clinical care.

18 - 85 years of age All Phase N/A

Intragastric Balloon in Obese Patients With Uncontrolled Asthma

The aim of this project is to study the effect of an intragastric balloon (IGB) on asthma control in obese patients. Obese patients with uncontrolled asthma will be recruited and randomly assigned to two intervention arms : an intragastric balloon combined with diet and exercise versus diet and exercise alone …

18 - 65 years of age All Phase N/A
C Crystal Malone, BSc

Tezepelumab in Allergic Rhinitis and Asthma Study (TEZARS)

The goal of this clinical trial is to learn about how well tezepelumab (pronounced TEZ e PEL ue mab), a Health Canada-approved drug for severe asthma, works in participants with coexisting allergic asthma and allergic rhinitis (hayfever). The main questions it aims to answer are: How well does the study …

18 - 65 years of age All Phase 2
E Elena Austin, ScD

The Airports, Air Quality, and Asthma (AAA) Study

For children with asthma, exposure to indoor air pollution increases the risk of a serious asthma exacerbation, which can be life-threatening. Interventions aimed at improving indoor air quality, including use of a portable air cleaner with a high-efficiency particulate air (HEPA) filter, can reduce this risk, but the effectiveness, feasibility …

6 - 12 years of age All Phase N/A

Community Health Equity Accelerator (CHEA) Pediatric Asthma Intervention

The purpose of this pilot is to initiate an academic-community partnership and launch a multi-level intervention that includes an asthma exposure pathway (an online decision support and resource) and a health Promotora program that will provide culturally responsive asthma support alongside legal and medical services to improve access to asthma …

4 - 11 years of age All Phase N/A
K Kalliopi Domvri, Dr

BenRalizumab Effect on Airway Remodeling in Severe asTHma

Response to biologic therapies in severe asthma is variable, with patients being either non-responders, responders or super-responders. There is currently no explanation for this broad variation in response. It is important to examine whether these patients have distinct characteristics that could help the treating physician in making the correct diagnosis …

18 - 85 years of age All Phase 4
J Job van der Palen, Full professor

Cohort Multiple Randomized Controlled Trial in Pediatric Asthma

The overarching goal of this study is to optimize pediatric asthma care and to continuously evaluate variations/innovations of the care (including transformation to remote eHealth care). Primary Objectives within cmRCT cohort: Provide a framework for multiple randomized (eHealth) interventions for asthmatic children Generate short- and long-term data on Quality of …

4 - 18 years of age All Phase N/A

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