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spinal-cord-disorders Clinical Trials

A listing of spinal-cord-disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 585 clinical trials

High Intensity Training for Neurological Injury Using Overground Exoskeletons in Inpatient Rehabilitation

The purpose of this study is to see if it's possible to reach high cardiovascular intensity training parameters (exercise at a rate that elevates heart rate to the level recommended for improving strength and endurance) while walking in a wearable robotic exoskeleton. This study will also evaluate if exercising at …

18 years of age All Phase N/A
R Randy D Trumbower, PT, PhD

Effects of Breathing Mild Bouts of Low Oxygen on Limb Mobility After Spinal Injury

Accumulating evidence suggests that repeatedly breathing low oxygen levels for brief periods (termed intermittent hypoxia) is a safe and effective treatment strategy to promote meaningful functional recovery in persons with chronic spinal cord injury (SCI). The goal of the study is to understand the mechanisms by which intermittent hypoxia enhances …

18 - 75 years of age All Phase N/A
S Steven Knezevic, MS

Seated Balance Using the Indego™

Exoskeleton-assisted walking (EAW) provides a new mobility option and appears to have potential therapeutic benefits for persons with SCI. However, present day technology is not sufficient to replace the wheelchair. During EAW, users stand upright, maintain static and dynamic balance by actively and passively stimulating trunk and lower limb muscles …

18 years of age All Phase N/A
L Lynsey Duffell, PhD

iCycle II: Recovery of Function Through FES Cycling With VR Biofeedback in People With SCI.

The annual incidence of traumatic spinal cord injury (SCI) is estimated at 2,500 (35 per week) in the UK and, due to advances in research and clinical management, the majority now have incomplete injuries, with significant potential for neurological improvement. Discovering ways to provide intensive, but cost-effective SCI rehabilitation is …

18 years of age All Phase N/A

Dosing of Overground Robotic Gait Training With Functional Outcomes and Neuroplasticity After Spinal Cord Injury

The DOOR SCI project examines dosing effects of robotic gait training (RGT) and transcranial magnetic stimulation (TMS) initiated during inpatient rehabilitation and continued through early outpatient rehabilitation

16 - 85 years of age All Phase N/A
I Ines Bersch-Porada

Investigation Into Optimal FES Training Characteristics After Spinal Cord Injury

The aim of this study is to investigate two different modalities of functional electrical stimulation (FES) leg exercise in patients with spinal cord injury (SCI). The primary outcomes being compared are 1. FES-induced leg aerobic fitness, and 2. FES-induced leg strength. There will be two FES-leg training groups, and sub-acute …

18 - 75 years of age All Phase N/A
S Shivayogi V Hiremath, PhD

Using Smartphones to Improve Physical Activity Levels of Individuals With Spinal Cord Injury

The overarching goal of this research study is to evaluate a sensor-enabled, just-in-time adaptive intervention (JITAI) strategy to increase and sustain physical activity levels among individuals with spinal cord injury (SCI) in their communities. A primary objective of this study is to evaluate the integration of a JITAI with a …

18 - 75 years of age All Phase 2
Y Yu-Chen Chen

Epidural Electrical Stimulation for Spinal Cord Injury Patients and Corticospinal Motor Circuit Improvement

The study aims to examine the plausible interventional mechanisms underlying the effects of epidural spinal cord stimulation.

20 - 70 years of age All Phase N/A
U Ufedo Miachi

Upper Limb Spinal Cord Stimulation for Rehabilitation Enhancement

In the United Kingdom, there are more than 1000 new cases of spinal cord injury (SCI) each year, with around half of these injuries affecting the cervical spine. People who have reduced function and control affecting their upper limbs may have difficulty carrying out activities of daily living (ADLs), significantly …

18 years of age All Phase N/A
J Jaclyn MIller, PT, DPT

Influence of Spinal Stimulation Frequency on Spasticity, Motor Control, and Pain After Spinal Cord Injury

The goal of this study is to identify the effect of different types of noninvasive spinal stimulation on spasticity (involuntary muscle activity), muscle strength, and pain in people with spinal cord injury. The spinal stimulation consists of electrical stimulation applied through one electrode over the skin of the lower back …

16 years of age All Phase N/A

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