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spinal-cord-disorders Clinical Trials

A listing of spinal-cord-disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 584 clinical trials
A Anna MacDowall, MD, PhD

Fusion or no Fusion After Decompression of the Spinal Cord in Patients With Degenerative Cervical Myelopathy

Background Degenerative cervical myelopathy (DCM) is characterized by neck pain, neck stiffness, weakness, paresthesia, sphincter disturbance and balance disorder. The mean age for symptoms is 64 years and more men than women, 2.7:1, are affected. The most common level is C5-C6. DCM is the predominant cause of spinal cord dysfunction …

18 - 100 years of age Both Phase N/A
D David Darrow, MD MPH

Epidural Stimulation After Neurologic Damage: Long-Term Outcomes

This study will evaluate the long-term effect of chronic spinal cord stimulation to restore volitional movement for patients with chronic spinal cord injuries.

22 - 100 years of age Both Phase N/A
G Ghaith J Androwis, Ph.D.

Combining Wearable Robotic Orthosis With Visual and Haptic Feedback to Enhance the Recovery of Upper Extremity Motor Function and ADL in Persons With Acute SCI

This randomized clinical trial (RCT) is evaluating the usefulness of combining MyoMo robotic orthosis with visual and haptic feedback in ameliorating wrist/hand/UE movement capability, and increasing ADL and quality of life in people with acute SCI.

18 - 80 years of age Both Phase N/A
D Dan Ding, PhD

Evaluation of Vision-Guided Shared Control for Assistive Robotics Manipulators

The purpose of this study is to evaluate a new control (i.e., the vision-guided shared control) for a wheelchair-mounted assistive robotic manipulator among powered wheelchair users. This study will consist of a questionnaire about general demographics, health information, and previous experience with assistive technology. Several tests will also be administered …

18 - 100 years of age Both Phase N/A
S Sydney Bader, MS

Spinal Cord Stimulation in Spinal Muscular Atrophy

Spinal cord stimulation (SCS) has shown remarkable efficacy in restoring motor function in people with spinal cord injury by recruiting afferent input to enhance the responsiveness of spared neural circuits to residual cortical inputs. This pilot will test if SCS can show evidence to improve motor deficits in people with …

16 - 64 years of age Both Phase N/A
Y Ying Fu, PhD

Rituximab for HTLV-1-associated Myelopathy

Neuroprotective or anti-inflammatory strategies are invaluable in HTLV-1-associated myelopathy due to its rapid progression. We evaluated the efficacy of rituximab in patients with HTLV-1-associated myelopathy.

18 - 80 years of age Both Phase 2

Improving Bowel Function and Quality of Life After Spinal Cord Injury

Bowel dysfunction is consistently rated as one of the most common complications affecting daily life for individuals with spinal cord injury. The overall objective of this study is to investigate whether the use of specific spinal cord epidural stimulation will affect bowel function. This study will also examine how alterations …

18 - 75 years of age Both Phase N/A
T Tamsyn Street, PhD

Electrical Stimulation of Abdominal Muscles for Bowel Management in People With Spinal Cord Injury

A well-managed bowel program is an essential part of daily life for many people with a SCI. Nevertheless, constipation is frequently reported (42-95%). Constipation embraces a spectrum of harms including both physical & psychological distress. Initial exploratory studies suggest abdominal FES may be useful for decreasing overall bowel management time, …

18 - 100 years of age Both Phase N/A
B Benjamin Davies

Quantiative MRI and Myelin-PET for the Assessment of Degenerative Cervical Myelopathy

To use advanced imaging techniques, including MRI Brain and Spinal Cord, and MRI/PET Spinal Cord to provide an assessment of Degenerative Cervical Myelopathy to improve understanding of the pathophysiology and natural history of DCM.

18 - 100 years of age Both Phase N/A
J Jessica Cantillo-Negrete, PhD

Efficacy of a Brain-Computer Interface Controlled Functional Electrical Stimulation Therapy for Spinal Cord Injury Neurorehabilitation

The study's main goal is to determine the efficacy of a therapy with brain-computer interface controlled functional electrical stimulation for neurorehabilitation of spinal cord injury patients' upper limbs. For this purpose, a randomized controlled trial will be performed to compare the clinical and physiological effects of the brain-computer interface therapy …

18 - 100 years of age Both Phase N/A

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