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diabetic-foot-ulcers Clinical Trials

A listing of diabetic-foot-ulcers medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 103 clinical trials
J Jonas Thomassen

Additional Hyperbaric Oxygen After Lower Extremity Amputation

This study evaluates the effect of additional hyperbaric oxygen therapy after lower extremity amputation. The patients will be randomized after amputation to either a treatment group receiving hyperbaric oxygen therapy, or control group.

18 - 90 years of age Both Phase N/A
M Matthieu Roustit

Prostacyclin (PGI2) Pathway to Enhance Wound Healing in Diabetic Foot Ulcers

Prospective, monocentric, pathophysiological study, comparing 3 parallel groups: healthy controls; patients with diabetes and without DFU; patients with diabetes and with DFU. To address secondary objectives, samples from a fourth group will be collected.

18 - 100 years of age Both Phase N/A
S Seokha Yoo, MD

Dose-finding Study: Popliteal Sciatic Nerve Block in Patients Undergoing Diabetic Foot Surgery

The purpose of this study was to determine the minimum effective dose of a local anesthetic for proper anesthesia for popliteal sciatic nerve block under ultrasound guidance in patients undergoing surgery for diabetic foot disease.

19 - 80 years of age Both Phase N/A

Toe Amputations in Patients With Diabetes

This study is a randomized controlled trial (RCT) to evaluate outcome after toe amputation due to diabetic foot infection. Aim of this RCT is to evaluate wound healing and functional outcome based, whether wound is closed or left open. As a part of this study, emerging technology of thermal imaging …

18 - 100 years of age Both Phase N/A
G Gayana Sarkisova, CCRC

Matrion™ Decellularized Placental Membrane in Subjects With Diabetic Foot Ulcers

In this study, a novel placental membrane product Matrion™ (LifeNet Health, Inc., Virginia Beach, VA) will be used as a treatment for subjects with diabetic foot ulcers. Matrion is composed of placental membrane derived from donated human birth tissue containing both the innermost amniotic layer and the outermost chorionic layer, …

21 - 80 years of age Both Phase N/A
H Hady K Elkhayat, Resident

Comparison Between Negative Pressure Wound Therapy and Conventional Wound Dressings Before and After Split-Thickness Skin Grafting in Diabetic Foot Wounds

The aim of this thesis is to compare the efficacy of Vacuum assisted closure device versus conventional dressing before and after split thickness skin grafting in diabetic foot wounds.

20 - 75 years of age Both Phase N/A
S Stewart R Walsh, FRCS

MetaMet: Bone Cutter Versus Bone Saw for Ray Amputation

Toe amputation is a commonly performed operation for infection and/or ischaemia (tissue death due to lack of blood flow). However, a large number of patients having this surgery ultimately require further amputation due to poor wound healing, new infections and/or new ulcers. Research to date has focused on patient-related factors …

18 - 100 years of age Both Phase N/A
P Philippe DOUEK, MD

Comparison of Imaging Quality Between Spectral Photon Counting Computed Tomography (SPCCT) and Dual Energy Computed Tomography (DECT)

This pilot study wants to determine to which extent SPCCT allows obtaining images with improved quality and diagnostic confidence when compared to standard Dual Energy CT (DECT), both with and without contrast agent injection. Depending on the anatomical structures/organs to be visualized during CT examinations, different scanning protocols are performed …

18 - 100 years of age Both Phase N/A
J Jacob Haus, PhD

Non-weight Bearing Exercise for Accelerated Healing of Diabetic Foot Ulcers

The goal of this study is to improve the therapeutic management of diabetic foot ulcers (DFU). The main questions to answer are if a program of non-weight bearing exercise helps the DFU heal faster than standard wound care. This randomized clinical trial will determine how blood flow to the ulcer …

18 - 75 years of age Both Phase N/A
V Vincent Giacalone

Bacteriophage Therapy in Patients With Diabetic Foot Osteomyelitis

This is a phase IIa randomized trial designed to evaluate bacteriophage therapy in patients with diabetic foot osteomyelitis.

18 - 85 years of age Both Phase 2

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