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Stroke Clinical Trials

A listing of Stroke medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,429 clinical trials
Z Zhongfan Ruan

Endovascular Treatment for eXtra-Large Ischemic Stroke

The role of endovascular thrombectomy in patients with extra-large ischemic burden is still unclear. The XL STROKE-2 randomized trial is aiming to investigate the efficacy and safety of mechanical thrombectomy in acute extra-large ischemic stroke patients with large vessel occlusion.

18 years of age All Phase N/A
L Lena Geiger-Primo, MD

Cognitive Recovery After Post Stroke Delirium (RECOVER)

RECOVER is a Proof-of-Concept study on cognitive functioning following a longitudinal design with three measurements (during the acute- and post-acute phases of a stroke and a 3-month follow-up) and two equally-sized stroke patient groups: a post-stroke delirium(PSD), and a non-PSD group (control group). Cognitive functioning will be assessed using a …

60 years of age All Phase N/A
E Evan Burr, BA

Mechanisms of Visual Restoration After Occipital Stroke

This project will collect brain imaging data to quantify the effects of early visual cortex damage and visual training interventions on the structure and function of the residual visual system. Our goal is to improve understanding of the consequences of permanent visual cortex damage in humans, and to understand how …

21 - 80 years of age All Phase N/A
J Jichang Luo

MPR for Stroke Risk Assessment of ICAS

Intracranial atherosclerotic stenosis (ICAS) carries substantial stroke risk despite optimal medical treatment. Current risk stratification relies primarily on stenosis severity, but novel hemodynamic markers may improve prediction. In this multiple prospective registry study we aim to investigate whether regional hemodynamics, measured by a novel Magnetic resonance imaging-derived Pressure Ratio (MPR) …

18 - 80 years of age All Phase N/A
B Beverly Allen, BS

Utility of CC7 Transfer in Stroke Subtypes

The purpose of this study is to evaluate the limb functional improvement after contralateral C7 root transfer in stroke patients.

18 - 65 years of age All Phase N/A
Y Yea-Ru Yang, PhD

High Intensity Interval Training in Chronic Stroke

Both gait and cardiovascular dysfunction are primary factors limiting community ambulation for stroke individuals. Increased gait variability and asymmetry contributes to a higher risk of falls, leading to reduced physical activity, decreased cardiorespiratory endurance, and increased walking economy and sympathetic nervous system activity, thereby potentially triggering secondary strokes. Previous studies …

18 - 69 years of age All Phase N/A
M Mark Bowden, PhD. PT

AFO Prescription to Optimize Post-Stroke Function

The overall goal of this study is to attain the highest possible health-related quality of life for individuals with lower-limb impairment through a clinical trial examining three different modern carbon fiber ankle-foot orthosis (AFO) treatment options targeting the rehabilitation of individuals post-stroke. To achieve this goal, the investigators will: Identify …

18 years of age All Phase N/A
R Ruijie Ma

Electroacupuncture Treatment for Post-stroke Cognitive Impairment

Stroke is a global public health issue, and it has become a leading cause of death and disability in China. With the rapid aging of the Chinese population, its incidence rate is continuously rising. According to the "China Stroke Prevention and Treatment Report (2023)", on average, one person experiences a …

35 - 80 years of age All Phase N/A
D Dana Moser, PhD, CCC-SLP

Treatment Outcomes With tDCS in Post-Stroke Aphasia

The purpose this study is to test the utility of pairing external neuromodulation with behavioral language treatment to boost therapy outcomes and to investigate the mechanisms associated with recovery. Because all PWA have word retrieval deficits, this project will test if greater language gains can be achieved by supplementing anomia …

18 - 80 years of age All Phase N/A
S Sameer Ansari, MD, PhD

Predicting Stroke Risk in ICAD With Novel MRI

The cerebral and spinal vasculature possesses several unique properties: it is composed of relatively small vessels, it has a highly connected network architecture, and, due to the confined space around the brain, disruptions in flow (rupture, shunting, or blockage) can cause a clinical impact quickly. These features apply across various …

18 - 85 years of age All Phase 4

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