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Stroke Clinical Trials

A listing of Stroke medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,489 clinical trials
S Samar Ayache, MD, PhD

EXOPULSE Mollii Suit, Motor Function & Stroke (EXOSTROKE)

Spasticity is a common and debilitating complication in neurological conditions such as multiple sclerosis, cerebral palsy, and stroke. Stroke, a leading cause of global disability and death, occurs when blood flow to the brain is disrupted, causing neuronal damage. Approximately 80% of strokes are ischemic, with 20% being hemorrhagic. Several …

18 - 75 years of age All Phase N/A
r ruijun Ji ruijun Ji

Efficacy and Safety Study of Ultra-early Mobile Stroke Unit Neuroprotection Combined With Revascularization for Acute Ischemic Stroke (EXCELLENT)

EXCELLENT was a prospective, multicenter, randomized, double-blind, placebo-controlled clinical study in which participants were randomized participants were randomized (1:1) to receive either IV thrombolysis + edaravone or IV thrombolysis + matched placebo (same volume of tablets without drug components), and the primary outcome was the proportion of patients with transformed …

18 - 80 years of age All Phase 4
P Petr Kolar, MD, PhD

Gait Recovery in Patients After Acute Ischemic Stroke

More than 80% of ischemic stroke (IS) patients have some walking disability, which restricts their independence in the activities of daily living. Physical therapy (PT) significantly contributes to gait recovery in patients after IS. However, it remains unclear, what type of gait training is more effective and which factors may …

18 - 80 years of age All Phase N/A
L Lisanne M Baak, MD

Darbepoetin for Ischemic Neonatal Stroke to Augment Regeneration

The aim of the study is to perform a randomized double-blind placebo controlled prospective study in newborn infants with MRI confirmed Middle Cerebral Artery (MCA) Perinatal Arterial Ischemic Stroke (PAIS) with darbepoetin. It will be investigated whether intravenous administered darbepoetin can induce the formation of neuronal tissue and restore brain …

- 7 years of age All Phase 2
C Chou-Ching Lin, MD, phD

Combined taVNS and tDCS in Subacute Stroke Patients

Ischemic stroke, the most prevalent neurological disorder, is treated with medication and thrombectomy but with limited success, especially in chronic stages where traditional rehabilitation is the primary option. Stroke often leads to post-stroke autonomic imbalance, deteriorating functional outcomes and increasing recurrence risk. Emerging non-pharmacological treatments like Transcutaneous Auricular Vagus Nerve …

18 years of age All Phase N/A
Y Yi Yang

Safety and Efficacy of Levofloxacin for Acute Ischemic Stroke

The purpose of this study is to determine the efficacy and safety of levofloxacin in treating acute ischemic stroke.

18 - 75 years of age All Phase N/A
G Ghaith J Androwis, Ph.D.

EMAGINE 2.0 - Electromagnetic Field Ischemic Stroke - Novel Subacute Treatment

This is a multicenter study that will be conducted at approximately 20 centers and up to 30 centers, if the sample size will be increased following interim assessment. The Q Therapeutic System (BQ 3.0) is a wearable medical device that produces and delivers non-invasive, extremely-low-intensity and low-frequency, frequency-tuned electromagnetic fields …

22 - 80 years of age All Phase N/A
N Nicole Bayus, MA

MiGo Tracker Remote Monitoring of Home Exercise After Stroke

This project will determine the safety and effectiveness of a MiGo Tracker RTM program in a randomized controlled trial with individuals with subacute stroke (N=50). Participants will be randomly assigned to either the MiGo Tracker RTM program (intervention group) or prescription of home exercises with no monitoring (usual care/control group). …

18 years of age All Phase N/A
H Hongguo Dai

BXOS110 Injection in the Treatment of Acute Ischaemic Stroke

The purpose of this study was to evaluate the effectiveness of early administration of BXOS110 for injection in reducing overall disability in patients with acute ischaemic stroke.

18 - 85 years of age All Phase 2
C Chuan Qin, MD

The Safety and Efficacy of NouvSoma001 in Ischemic Stroke

This is a single-center, randomized, open-label, placebo-controlled, dose-escalation trial. The objective of this research is to evaluate the safety, tolerability, and preliminary efficacy of intravenous administration of human-induced neural stem cell-derived extracellular vesicles (NouvSoma001) in the treatment of ischemic stroke.

18 - 75 years of age All Phase 1

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