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Stroke Clinical Trials

A listing of Stroke medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,489 clinical trials
M Meng Ting Lin, M.D.

Neuromodulation Effect of Focused Ultrasound for Motor Recovery in Patients With Stroke

Transcranial focused ultrasound (tFUS) can be used as a non-invasive brain neuromodulation technique. Low-intensity focused ultrasound has been demonstrated to be safe and have neuromodulatory effects on the cerebral cortex in healthy human and animal experiments.This study aims to investigate the effect of tFUS on cortical excitability for motor recovery …

18 years of age All Phase N/A
A Anders S West, MD, PhD

The Effects of Naturalistic Light on Post Stroke Complications Related Brain Areas in Stroke Patients During Admission for Rehabilitation.

Background Light is the most important regulator of circadian rhythm. Naturalistic light, which contains the spectrum of sunlight throughout the day, has been shown to have a positive impact on mental states such as depression and fatigue in stroke and other diseases requiring long-term hospitalization. Depression and fatigue are very …

18 years of age All Phase N/A
M Mansoo Ko, Ph.D

Optimizing Gait Symmetry After Stroke Using Mechanical Constraints and Sensory Feedback

This single-session study aims to evaluate a novel gait training protocol that integrates mechanical constraints and sensory feedback to enhance paretic leg propulsion in individuals post-stroke. The study will include 15 individuals who have experienced a stroke and 15 healthy adults, each aged 20 years or older. Participants will walk …

20 years of age All Phase N/A
P Parneet Grewal, MD

Accelerated rTMS vs. Sham for Stroke Apathy

Apathy is a common set of symptoms seen in many people following a stroke. Apathy occurs when a person has lost motivation, becomes withdrawn, and stops doing things that used to be important to them. Apathy has a large negative impact on a person's quality of life, and can also …

40 years of age All Phase 1/2
J James S Sulzer, PhD

Reflex Excitability in Post-stroke Stiff-Knee Gait

The purpose of this study is to examine the reflex excitability of the rectus femoris in individuals with and without post-stroke Stiff-Knee gait. We use electrical stimulation of the peripheral nerve innervating the rectus femoris for a well-controlled reflex stimulus. We are investigating whether reflex excitability of the rectus femoris …

18 years of age All Phase N/A
J Jow Harbison, MD

Investigating the Use of a Brain-computer Interface Based on TMS Neurofeedback for Upper Limb Stroke Rehabilitation

The mechanisms and effectiveness of a technique to boost the brain's recovery mechanisms will be studied. Brain-Computer Interface (BCI),based on applying magnetic pulses (Transcranial Magnetic Stimulation, TMS) to the stroke damaged area in the brain, causing twitches in the paralysed muscles will be used. The size of these twitches are …

18 years of age All Phase 1
L Lisa C Krishnamurthy, PhD

Biomarkers of Reaction To HIIT Exercise

Stroke survivors with lower limb disability can improve their walking speed with high-intensity interval training (HIIT) rehabilitation therapy. However, some individuals may not respond to HIIT even when fully adherent to the program. To address this, the investigators propose to build a predictive model that identifies if a Veteran with …

18 - 80 years of age All Phase N/A
K Katja Drost, Drs.

Effect of Occupational Therapy at Home E-Rehabilitation (OTHER) for Persons Post-stroke

The goal of this (cost)effectiveness study is to compare care as usual with OTHER-intervention in Cerebro Vascular Accident (CVA) older adults in Geriatric Rehabilitation (GR). The main question[s] it aims to answer are: What is the effectiveness of OTHER, as compared to occupational therapy as usual (CAU), on improving the …

60 years of age All Phase N/A
J Jennifer Majersik, MD, MS

Promoting Resilience in Stroke Survivor-carepartner Dyads (ReStoreD)

Affecting nearly 800,000 people in the US every year, stroke is a leading cause of long-term disability, and has serious consequences for stroke survivors and their carepartners. Our project uses a scientifically rigorous efficacy study to evaluate a remotely delivered 8-week dyadic (couples-based) positive psychology intervention to reduce emotional distress …

18 years of age All Phase N/A
P Ph.D

Construction and Effect Evaluation of Integrated Care Model for Pulmonary Infection in Stroke Patients With Tracheotomy

To understand the occurrence of pulmonary infection in stroke patients with tracheotomy, and to clarify the current situation of clinical nursing. Construct a standardized, systematic and scientific integrated care model to control the severity of pulmonary infection in non-acute stroke patients with simple tracheotomy. To evaluate the clinical application effect …

18 - 100 years of age All Phase N/A

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