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Stroke Clinical Trials

A listing of Stroke medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,522 clinical trials
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Effects of Intensive Training on Reocvery of Fingers Dexterity Following Stroke

The investigators aim to test whether intensive training of finger individuation during the sensitive window of the subacute phases can lead to a clinically-meaningful recovery of dexterous movement in stroke patients.

20 - 85 years of age All Phase 1/2
G Giada Devittori, M. Sc.

Unsupervised Therapy After Stroke in the Home Setting With a Hand Rehabilitation Device (ReHandyBot)

The ReHandyBot is a robot for hand rehabilitation after stroke. The aims of this study are (1) to investigate the feasibility of unsupervised therapy with the ReHandyBot with stroke inpatients, first in a rehabilitation clinic and then at participants' home, (2) to evaluate the usability of the ReHandyBot (user interface, …

18 - 90 years of age All Phase N/A
Z Zaza Putkaradze, PharmD

Regenerative Stem Cell Therapy for Stroke in Europe 1-RESSTORE1

Stroke is the second leading cause of death in the world population. When not fatal, stroke often results in disability, and secondary health problems affecting not only patients but also their families. Building on emerging preclinical and pilot clinical evidences, RESSTORE will focus on the clinical assessment of regenerative cell …

18 years of age All Phase 1
D Daniel Bustos, PT

ExoDoF: Robotic Exoskeleton for Upper Limb Motor Rehabilitation After Stroke

Two decades ago, the projection of recovery of the upper extremity (UE) after a stroke had a very poor prognosis worldwide. Nowadays, thanks to medical advances and early rehabilitation, the prognosis for recovery has improved; however, there is still a limit that no therapy has been able to overcome, related …

18 - 81 years of age All Phase N/A
R Raymond Tong, PhD

Soft Robot for Rehabilitation of Hand Function After Stroke

The goal of this clinical trial is to investigate the feasibility of using the Soft Forearm Robot system for wrist and forearm recovery of hemiplegic subjects suffered from stroke. Participant will attend 20 training sessions and 3 assessment sessions. This system will leverage electromyography (EMG) signals for intention detection and …

18 years of age All Phase N/A
F Francesca Burgio, PhD

Integrating AI in Stroke Neurorehabilitation

The AISN multicenter randomized controlled trial will assess the effectiveness of a novel artificial intelligence (AI)-based clinical decision-support system integrated into the Rehabilitation Gaming System (RGS) for home-based post-stroke rehabilitation. Approximately 192 participants ≥6 months post-stroke will be recruited across several European centers and assigned to one of three groups: …

18 years of age All Phase N/A
Y Yongjun Wang

Tenecteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events-BEYOND

The benefit-risk profile of thrombolysis for acute ischemic strokes beyond 24 hours has never been investigated. We initiated a multicenter, prospective, randomized, open label, blinded-endpoint (PROBE) controlled trial to assess the safety and efficacy of tenecteplase (0.25mg/kg, max 25mg) versus standard medical treatment in acute ischemic stroke due to large …

18 years of age All Phase 3

Combined Effects of Soft Robotic Hand and Electrical Stimulation on Hand Function in Stroke Survivors

Stroke is a clinically delineated syndrome, which is characterised by an acute, focal neurological deficit resulting from vascular injury (infarction or haemorrhage) within the central nervous system. Notably, around 80 percent of stroke survivors experience post-stroke deficits in upper extremity (UE) motor performance, impacting grip strength, dexterity, and functional independence, …

45 - 65 years of age All Phase N/A
C Cira Fundarò, MD

Effects of Trans-Auricular Vagal Stimulation on Neuromotor Recovery in Subacute Stroke During Technological and Traditional Training

This randomized pilot clinical study aims to investigate the effects of trans-auricular vagus nerve stimulation (tVNS) on neuromotor recovery in patients in the subacute phase after stroke. Participants admitted for intensive rehabilitation at ICS Maugeri Centers (Montescano, Pavia, Nervi) will be randomized into four groups receiving either traditional or technological …

18 years of age All Phase N/A
J Jingsong Wu

Robot-Assisted Tai Chi for Upper Limb Rehabilitation in Stroke Patients

This study aims to compare the effectiveness of Robot-Assisted Tai Chi Training (RATT) versus conventional rehabilitation in improving upper limb motor function post-stroke, and to explore the neuromuscular mechanisms of RATT. Participants will be randomly assigned to one of two groups: Robot-Assisted Tai Chi Training group: Participants will receive guided …

40 - 80 years of age All Phase N/A

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