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heart-disease Clinical Trials

A listing of heart-disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,908 clinical trials
A Ali Shariat, M.D.

Rectus Sheath Block in Cardiac Surgery

This is a prospective, randomized study. The purpose of this study is to evaluate the effect of post-surgical pain control of a type of peripheral nerve block, Rectus Sheath Block. Does the rectus sheath block decrease opioid consumption postoperatively after cardiac surgery? Does the rectus sheath block decrease VAS pain …

18 - 85 years of age All Phase N/A
C Carina Platte, PhD

Smart Walk: A Culturally Tailored Smartphone-Delivered Physical Activity Intervention for African American Women

The purpose of this study is to test a culturally tailored, smartphone-delivered intervention designed to increase physical activity and reduce risk for heart disease and type 2 diabetes among African American women.

24 - 65 years of age Female Phase 2

Cerebral Oxygen Saturation Monitoring In Cardiac Surgery (COSMICS)

Neurological dysfunction continues to be one of the complications of considerable concern in patients undergoing cardiac surgery. It was previously reported in the literature, that cerebral oxygen desaturation during cardiac surgery was associated with an increased incidence of cognitive impairment. This study aims to determine whether continuous monitoring of cerebral …

60 years of age All Phase N/A
R Research Coordinator

Left Bundle Branch Area Pacing (LBBAP) PMCF Study

The objective of this study is to evaluate the safety and effectiveness of LBBA pacing/sensing in patients implanted with the Tendril STS 2088TC or UltiPace LPA1231 lead through 6 months post-implant.

18 years of age All Phase N/A
J Jonathan Derr, MBA

Dilated Cardiomyopathy Detection Using AI and Screening With Mobile Technology (DCM-DETECT)

This is a prospective, single-arm clinical trial in which participants with dilated cardiomyopathy will invite their first degree relatives to undergo mobile cardiac, electrocardiogram screening.

18 years of age All Phase N/A
G Greg Marcus

Gauging Outcomes of Total Milk Ingestion on Lipid and gControl

Atherosclerotic cardiovascular disease remains the leading cause of death for adults in the United States. The cardiovascular impact of milk consumption remains a matter of long-standing scientific debate. Current guidelines for Americans recommend three daily servings of fat-free or low-fat (1%) dairy over full-fat options due to concerns that saturated …

18 years of age All Phase N/A

PREhabilitation in Patients Awaiting Acute Inpatient Cardiac SurgEry

This is a single centre, single arm pilot feasibility study to determine the feasibility and practicality of prehabilitation in acute inpatients waiting for cardiac surgery. We will be looking into participant eligibility, acceptability, recruitment rates, completion rates and barriers to implementing a prehabilitation programme. Secondary outcomes include safety (incidence of …

18 years of age All Phase N/A

Effectiveness of Continuous Glucose Monitoring System Among Cardiac Surgery Patients

The aim of this study is to assess the level of glycemic control and the incidence of surgery-related complications in cardiac patients post-surgery when Continuous Glucose Monitoring (CGM) is utilized, as compared to traditional methods of arterial/venous blood sampling and Point-of-Care Testing (POCT) for glucose monitoring.

18 years of age All Phase N/A
S Saad Javed

Therapy to Maintain Remission in Dilated Cardiomyopathy

One third of patients diagnosed with heart failure demonstrate left ventricular reverse remodelling and recovery of cardiac function following a period of medical therapy. The TRED-HF trial investigated the impact of therapy withdrawal in this cohort and found that 40% of patients relapsed within 6 months of stopping treatment. In …

18 - 85 years of age All Phase N/A

Accuracy of LAA Occluder Size Selection: CT vs. DSA During Combined AF Ablation and LAA Occlusion

This study is a prospective, multi-center, randomized controlled trial. The subjects are patients scheduled to undergo a combined procedure of atrial fibrillation (AF) ablation and left atrial appendage (LAA) occlusion. After signing the informed consent form, the subjects will be randomly assigned to either the cardiac Computed Tomography (CT) group …

18 years of age All Phase N/A

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