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Anxiety Disorders Clinical Trials

A listing of Anxiety Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 928 clinical trials
S Sophie Boutouis, BS

A Clinical Trial of Tolcapone in Obsessive Compulsive Disorder

The primary aim of the present study is to examine the efficacy and safety of tolcapone in adults with moderate to severe OCD.

18 - 65 years of age All Phase 2
M Martijn Figee

Connectomic Deep Brain Stimulation for Obsessive Compulsive Disorder

Deep brain stimulation (DBS) is an effective treatment for people suffering from severe obsessive-compulsive disorder (OCD) whose symptoms have failed to improve after years and multiple methods of intervention. An effective DBS target for OCD is the anterior limb of the internal capsule (ALIC) brain region. On average 60% of …

18 years of age All Phase N/A
D Dr. Randi McCabe, PhD

Mindfulness-Based Interventions for OCD

Obsessive-compulsive disorder (OCD) is a severe and debilitating anxiety disorder afflicting about 2% of the population. It is characterized by the presence of recurrent obsessions and/or compulsions that are time consuming and cause marked distress and/or impairment. Untreated, OCD runs a chronic and deteriorating course. According to the World Health …

18 - 65 years of age All Phase N/A
C Christine Conelea, PhD

TMS + Exposure Therapy for Pediatric OCD

The goal of this clinical trial is to compare different forms of transcranial magnetic stimulation (TMS) for improving the outcomes of Exposure with Response Prevention (ERP) in youth and young adults with Obsessive-Compulsive Disorder (OCD). Researchers will compare three groups: ERP with one of two different active ("real") forms of …

12 - 21 years of age All Phase N/A
A Andrew M Lee, MD, PhD

Cortical Stimulation to Treat Obsessive Compulsive Disorder

The purpose of this study is to identify abnormal brain signals associated with Obsessive Compulsive Disorder (OCD) and psychiatric symptoms and to investigate novel therapeutic stimulation sites. While treating OCD with standard deep brain stimulation (DBS) therapy, the investigators will also monitor the activity of the anterior cingulate and prefrontal …

22 - 75 years of age All Phase N/A
M Mafalda Sousa, M. Sc.

iTreatOCD: Predicting the Efficacy of Internet-based Cognitive Behavioral Therapy in Obsessive-compulsive Disorder

In the current study, the investigators will characterize obsessive-compulsive disorder (OCD) patients and healthy controls with a comprehensive clinical and neuroimaging assessment, focusing on the basic psychological processes related and on the neurobiological underpinnings of emotion regulation (ER). After a baseline assessment, the investigators will implement an internet-based cognitive behavioral …

18 - 65 years of age All Phase N/A
S Susanne Walitza, Prof. Dr. med. Dipl.-Psych.

Short and Intensive Treatment of Children and Adolescents With Obsessive-Compulsive Disorder

Obsessive-compulsive disorders are very damaging illnesses; they can already appear in childhood and adolescence and become extremely chronic. With an average prevalence from 1-3%, they are among the most common psychiatric disorders in children and adolescents. 40% of diagnosed children and young adults display persistent and increasingly chronic symptoms and …

8 - 18 years of age All Phase N/A
G Ghina Harika-Germaneau, MD, PhD

Bilateral Lateral OFC rTMS in Obsessive Compulsive Disorder

According to the literature the lateral part of the Orbito Frontal Cortex (lOFC) is a relevant bilateral target for repetitive Trans-cranial Magnetic Stimulation (rTMS) in Obsessive Compulsive Disorder (OCD). Both hemispheres are concerned in terms of target.

18 - 65 years of age All Phase N/A
J Jenna Schugart

DBS for Obsessive-Compulsive Disorder

There are two primary approaches to the treatment of OCD, pharmacotherapy and cognitive behavior therapy (CBT). Lack of therapeutic success with one approach leads to trials of the alternative approach or a combination of the two. A rarely used third therapy approach, appropriate for only the most severely afflicted and …

18 years of age All Phase N/A

Efficacy of Augmentation of Cognitive Behavioral Therapy With Transcranial Direct Current Stimulation for Obsessive-Compulsive Disorder (OCD)

This study aims to evaluate the feasibility and clinical outcome of the Exposure-based Cognitive-Behavioral Therapy (CBT) concurrent with Transcranial Direct Current Stimulation (tDCS) in treating obsessive-compulsive disorder (OCD) patients, and explores the potential neural mechanisms of treatment effect by magnetic resonance imaging (MRI) and electroencephalography (EEG).

18 - 50 years of age All Phase N/A

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