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ocular-hypertension Clinical Trials

A listing of ocular-hypertension medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 99 clinical trials

Investigation of Neurovascular Coupling in Glaucoma Patients and Healthy Subjects

Glaucoma is characterized by a progressive loss of retinal ganglion cells (RGCs) leading to optic nerve head (ONH) damage and associated visual field defects. The main risk factor for glaucoma is elevated intraocular pressure (IOP). Reducing IOP slows down the progression of the disease as several large multicenter trials have …

18 years of age All Phase N/A
C Clinical Trial Lead

Direct Selective Laser Trabeculoplasty in Ethnic Chinese Population

The objective of this study is to evaluate the safety and effectiveness of Direct Selective Laser Trabeculoplasty (DSLT) in ethnic Chinese participants with Primary Open Angle Glaucoma (POAG), Ocular Hypertension (OHT), or Normal Tension Glaucoma (NTG).

21 years of age All Phase N/A
E Estela del Mar Sánchez Sotano

Evaluation of BRUDYGLAUCO (DHA + Citicoline) in Patients With Glaucoma

This study aims to evaluate the effects of BrudyGlauco, a nutritional supplement containing DHA (docosahexaenoic acid) and citicoline, on visual function in people with glaucoma. Glaucoma is a progressive optic neuropathy that can lead to vision loss. Current treatments focus on lowering eye pressure, but there are other pathogenic factors …

50 - 75 years of age All Phase N/A
M Mads Kristensen

Developing and Testing a Model to Identify Preventive Vision Loss Among Older Patients in General Practice

In this cohort study, the investigators will test vision screenings in Danish general practice for patients over 70 years of age with minimum one chronic condition. The main outcome is detection of vision impairment and secondary outcome is detection of conditions needing ophthalmologic follow-up but not presenting vision impairment at …

70 years of age All Phase N/A

Clinical Trial To Determine The Efficacy And Safety Of Insulin Eye Drops In Dry Eye In Patients With Topical Hypotensors

The goal of this clinical trial is to evaluate the preliminary efficacy of the use of insulin eye drops in the control of dry eye disease in patients with topical hypotensors, compared to placebo (artificial tears). The main question aims to answer whether glaucoma patients treated with topical hypotensors could …

18 years of age All Phase 4
Y Yu-Chen Lee, Ph.D.

Acupuncture as Adjuvant Therapy for Glaucoma - Protocol for a Randomized Controlled Trial

This clinical trial used acupuncture as an adjunctive treatment for glaucoma patients. A randomized, controlled trial involving 50 subjects will be conducted and observed for 12 weeks to evaluate the clinical efficacy of acupuncture. This study aims to provide a reference for future clinical treatment guidelines.

20 years of age All Phase N/A

Glaucoma Rehabilitation With Action viDeo Games and Exercise - GRADE

Falls are one of the most serious public health concerns for seniors, with significant medical and economic consequences. This concern is even higher in patients with peripheral field loss due to glaucoma because of the patients' compromised visual input. The investigators' project proposes an innovative, entertaining, easily accessible and enjoyable …

55 - 80 years of age All Phase N/A
S Study Team

Hyperbaric Oxygen Therapy for Optic Neuropathies

The purpose of the study is to evaluate the neuroprotective efficacy of hyperbaric oxygen for the treatment in patients with optic neuropathy.

18 years of age All Phase N/A
M Miriam Kolko, MD, Phd

A Study Investigating Oral Semaglutide in People with Open-Angle Glaucoma

The aim of this clinical trial is to investigate whether oral semaglutide can be used to treat open-angle glaucoma. The main question it aims to answer is: Does oral semaglutide safely improve inner retinal function in patients with open-angle glaucoma as measured by the photopic negative response of the electroretinogram. …

45 years of age All Phase 4
M Marie-Catherine Thessier, Msc

The Role of Transscleral Cyclophotocoagulation in Patients Undergoing a Boston Keratoprosthesis

The Boston keratoprosthesis (KPro) is a special plastic device that is used to replace a sick cornea (transparent part of the eye, in front of the iris) in order to restore vision in patients who have failed traditional corneal transplants or have a very poor prognosis of success. Glaucoma is …

18 - 80 years of age All Phase N/A

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