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aging Clinical Trials

A listing of aging medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 641 clinical trials
S Suzhen Wu, Professor

Effect of Korean Red Ginseng on Oxidation in Middle-aged and Elderly Sub-health Population

The objective of this study is to examine the effects and safety of Korean red ginseng capsule and placebo with middle-aged and elderly sub-health population.

40 - 75 years of age Both Phase 2/3
M Mary Emma Searles

Sleep-dependent Learning in Aging

The specific objective of this proposed research is to understand whether deficits in sleep-dependent memory changes reflect age-related changes in sleep, memory, or both. The central hypothesis is that changes in both memory and sleep contribute to age-related changes in sleep-dependent memory processing. To this end, the investigators will investigate …

18 - 75 years of age Both Phase N/A
Y Yiru Wang, MS PT

Aging and Mixed Perturbation Training to Reduce Falls in Locomotion

The long-term objective of this research is to develop an efficacious training paradigm to enhance older adults' defense mechanisms against falls and possibility reduce healthcare cost. The Centers for Disease Control and Prevention estimates the direct medical cost for fall related injuries to be $30 billion annually. Slips and trips …

60 - 90 years of age Both Phase N/A
Y Yeung Yuk Kwok

Adopting a Health-social Partnership Program to Promote Health and Self-care Management Among Older Adults in the Community

Hong Kong has notably the longest life expectancy in the world. Ever-increasing demand and challenges are posing to the healthcare, social welfare, and elderly care service system. As a global public health strategy to address the increasing burdens, there is a strong urge for an effective approach to enhance the …

60 - 100 years of age Both Phase N/A

A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer and Tabirafusp Tedromer Compared to Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD) - DAYBREAK

A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer and Tabirafusp Tedromer Compared to Aflibercept in Participants with Neovascular (Wet) Age-related Macular Degeneration (wAMD)

50 - 100 years of age Both Phase 3
K Keith Baker

A 2-part Study Consisting of Multiple Ascending Dose (MAD) Safety Study, and a Dose-finding Masked Study to Assess the Safety and Efficacy of Intravitreal (IVT) EYE103 in Patients With Diabetic Macular Edema (DME) or Neovascular Age-related Macular Degeneration (NVAMD)

EYE103-101 is a 2-part study assessing safety and preliminary efficacy of EYE103 in patients with diabetic macular edema (DME) given as monotherapy or neovascular macular degeneration (NVAMD) given in combination with anti-VEGF. In the first part, termed the multiple ascending dose (MAD) portion of study, the safety of EYE103 will …

50 - 100 years of age Both Phase 1/2
F Florence REMY, PhD

MRI and Eye-tracking Predictive Markers of Cognitive Ageing

This research proposes to investigate physiological and cognitive markers of locus coeruleus (LC) neuronal integrity and function in cognitively-healthy participants over 60 years old. The locus coeruleus is a brainstem nucleus, sole source of noradrenaline for the brain. Tau pathology appears in neurons of this nucleus, which may induce initial …

60 - 100 years of age Both Phase N/A
A Amy C Arnold, PhD

Angiotensin-(1-7) Cardiovascular Effects in Aging

Aging is an independent risk factor for developing hypertension and cardiovascular disease; however, the mechanisms underlying age-related cardiovascular disease remain poorly understood. One hallmark of aging is an increase in sympathetic nervous system activity, which can decrease the number and/or sensitivity of β2 adrenergic receptors to reduce dilation of blood …

65 - 80 years of age Both Phase N/A

Multimodal Musical Stimulation for Healthy Neurocognitive Aging

This is a Stage I randomized, sham-controlled trial on the effects of multimodal musical stimulation on working memory in aging. Neurologically healthy older and younger adults will be tested on working memory and electroencephalography in the first randomized controlled trial of music as a form of brain stimulation, with multimodal …

18 - 95 years of age Both Phase N/A
P Peter Mukli, MD, PhD

The Effect of NAD Supplementation on Brain Vascular Health in Aging

Daily consumption of one of the forms of Vitamin B3, the Nicotinamide Riboside (NR), energizes the body and combats cellular aging. This study is designed to test whether NR can also improve brain health and memory.

60 - 85 years of age Both Phase 4

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