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substance-abuse Clinical Trials

A listing of substance-abuse medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 541 clinical trials
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Understanding How Cigarette Direct Mail Marketing Influences Smoking Behaviors Among High and Low Socioeconomic Status Young Adult Smokers

Background Smoking is a major public health problem in the U.S. Almost a half a million Americans die from it in a year. One thing that contributes to why people smoke is the marketing of cigarettes. Cigarette direct mail marketing usually targets young smokers of lower socioeconomic status. Researchers want …

18 - 29 years of age All Phase N/A
C Carl Latkin, PhD

Social Network Overdose Prevention and Education Intervention

The purpose of this study is to test a social intervention focused on overdose prevention and care. In the investigators prior work, the investigators have shown that people who use opioids (PWUO) can be effective peer educators (PEs).

18 years of age All Phase N/A
J Jim Arinaitwe, MBcHB, MPH

Adapting and Evaluating a Tobacco Use Cessation Program for People Living With HIV in Uganda and Zambia

This proposal tests the efficacy of a phone-based tobacco cessation intervention for people living with HIV (PLWH) in comparison to the standard of care (brief advice to quit) and nicotine replacement therapy (nicotine patches) in Uganda and Zambia. This study will provide insight into the efficacy, feasibility, applicability, and affordability …

18 years of age All Phase 1
S Sandilyn Bullock, MPH

FRESH Delivers: An Innovative Approach to Reducing Tobacco Use Among Rural/Black African American Smokers

The long-term goal of FRESH Delivers is to fill a critical gap in knowledge on the role of a home-based food delivery social intervention in the elimination of tobacco-caused cancer health disparities. The central hypothesis is that smokers who receive real-time video-based motivational counseling and home-based food deliveries will have …

21 - 75 years of age All Phase N/A
J Jasmina MALLET, MD-PhD

Cohort Study on Medical Students' Mental Health

The main objective of this study is to identify risk factors for depression among medical students by comparing them to students who completed their first year but did not enter the medical program (students not accepted into the second year of medical school). Major Depressive Disorder (MDD) will be assessed …

18 years of age All Phase N/A
S Stacy Sterling, PhD

Centralized Virtual SBIRT for Pediatric Primary Care

Adolescent alcohol and other drug (AOD) use is a significant public health problem which contributes to high levels of mortality, morbidity and healthcare costs in young people, and identification and early intervention for these problems is critical to improving outcomes. Screening, Brief Intervention and Referral to Treatment (SBIRT) in pediatric …

12 - 17 years of age All Phase N/A
B Blake Andreou, BS

Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations

In the current study, the investigators aim to understand the role of transcranial direct current stimulation (tDCS) in improving executive function across neuropsychiatric populations known to have deficits in this cognitive domain.

18 - 65 years of age All Phase N/A
C Chelsey Schlechter, PhD

Reach Through Equitable Implementation in Utah

The goal of this pragmatic, multilevel Type III Hybrid Effectiveness-Implementation trial is to increase the reach of existing evidence-based interventions (EBIs) for tobacco cessation and to mitigate the impact of adverse Social Drivers of Health (SDOH) among safety-net healthcare system patients who live in persistent poverty (PP) census tracts. Aim …

18 years of age All Phase N/A
N Nicole Verdiglione, BA

iLookOut for Child Abuse: Micro-learning to Improve Knowledge Retention

This proposed randomized controlled trial will examine whether gamified micro-learning is a feasible and effective way to promote long-term learning about child abuse and its reporting. After completing the interactive online learning program, iLookOut for Child Abuse, early childhood professionals will receive brief (5-10 minute) gamified learning exercises to complete …

18 - 100 years of age All Phase N/A
N Nicole Verdiglione, BA

iLookOut for Child Abuse -Online Learning Module for Early Childcare Providers

Phase 1 was a randomized control trial that used a test-retest model to evaluate the impact of iLook Out for Child Abuse, an online, interactive learning module about reporting suspected child abuse. Delivered via a learning management system to early childhood professionals who work with infants and young children, this …

18 years of age All Phase N/A

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