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hiv-infections Clinical Trials

A listing of hiv-infections medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 464 clinical trials
O Orlando Martinez J Peer Navigator

Enhancing PrEP Uptake and Retention Among Latine TGW and GBM in the South Using Long-Acting Injectable PrEP

The purpose of this project is to test a culturally-tailored, community-delivered long-acting injectable PrEP (lenacapavir) program for Latine gay and bisexual men (GBM) and transgender women (TGW). The objective is to evaluate whether this intervention demonstrates greater persistence on lenacapavir for Latine GBM and TGW compared with what has been …

18 years of age Male Phase 4
Z Zane Guilfoyle, LPC, LAC, ACS, MAC, ADS

WePrEP: Developing a PrEP Shared Decision-making Tool for Transgender Women

HIV prevalence among transgender women (TW) in the United States is high (~14%). The best way to reduce HIV incidence in this population is to link TW to HIV pre-exposure prophylaxis (PrEP), which can reduce HIV transmission by up to 86%, with optimal adherence. The FDA approved the first long-acting …

18 - 65 years of age Male Phase N/A
K Karen Cropsey

Telemedicine for Unhealthy Alcohol Use in Persons Living With HIV Using CETA

This study is designed to examine the efficacy of a brief intervention plus a cognitive-behavioral intervention compared to brief intervention alone to address unhealthy alcohol use and comorbid mental health symptoms to improve HIV outcomes among people living with HIV in Alabama.

18 - 99 years of age All Phase N/A
A Ashley E Williams, MS

Universal Basic Income and Structural Racism in the US South: HIV Care

Universal Basic Income (UBI) is a promising strategy aimed at recalibrating economic systems that are grounded in structural racism. Black men have long been the target of oppressive and interconnected systems of finance and healthcare access, leading to a disproportionate burden of exposure to infectious disease with little healthcare support. …

25 years of age Male Phase N/A

Imaging and Biopsy of People With HIV-1 Undergoing Analytic Treatment Interruption

Background Human immunodeficiency virus (HIV) infects CD4 T cells. There is no cure for HIV. People with HIV need to take daily medications called antiretroviral therapy (ART) to control their infection. ART stops HIV from infecting cells, but HIV does not go away. Some infected cells remain. If ART is …

18 - 100 years of age All Phase 2

Neuroactive Steroid to Treat Depressed Mood: A Trial for People With HIV

This study will determine the effects of pregnenolone on brain function, inflammation and depressive symptoms in people with HIV who have depression. Participants in this study will receive a pill of either pregnenolone or placebo, and can stay on their current antidepression medications. Brain imaging and behavioral assessments will be …

18 - 85 years of age All Phase 2
M Marianna Wetherill, PhD

Nutrition to Optimize, Understand, and Restore Insulin Sensitivity in HIV for Oklahoma

The NOURISH-OK Study will identify how food insecurity contributes to insulin resistance, an important surrogate marker of many co-morbidities in HIV disease, using an integrated framework to identify key leverage points for insulin resistance. Drawing from these pathways, this study will adapt and evaluate a community-driven, science-informed "food as medicine" …

18 years of age All Phase N/A
R Rosa Chemwey, MBChB, MMed

Enhanced Mentor Mother Strategy for Pregnant and Postpartum Women Living With HIV

Mentor Mothers (MMs) are peer supporters who help pregnant and postpartum women living with HIV (WLHIV) as they receive prevention of mother-to-child transmission of HIV (PMTCT) services in resource-limited settings like Kenya. Differentiated service delivery (DSD) is a care model that tailors services based on clients' needs, helping to improve …

18 years of age Female Phase N/A
P Preeti Manavalan, MD

A Behavioral mHealth Intervention for People With HIV With Anxiety and Depression

This study will adapt and assess the preliminary effectiveness of a community health worker-delivered mental health counselling intervention delivered remotely to reduce anxiety and depression among people with HIV in Florida.

18 - 90 years of age All Phase N/A
L Lindsay T Fourman, MD

Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV

People with HIV experience earlier impairments in physical function compared to people in the general population. They also exhibit an earlier presentation and more rapid development of frailty, a multisystemic syndrome of aging characterized by reduced activity, fatigue, slowness, weakness, and weight loss. While exercise can improve physical function in …

50 - 80 years of age All Phase 2

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