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bone-fractures Clinical Trials

A listing of bone-fractures medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 401 clinical trials
E Emily Dunn, MSc

IM Screw vs. K-wire Fixation of Proximal/Middle Phalanx Fractures

When people break their fingers, sometimes surgery is needed to align the bones to heal them properly. There are different ways to fix broken bones in hands, such as plates, pins, or screws. Each method has pros and cons; fixing a broken bone with plates is usually a larger surgery …

18 years of age All Phase N/A
B Benedik J. Braun, PD. Dr. med.

Effect of Tobacco Heating System (THS) on Closed Tibia Fracture Healing

The goal of this clinical trial is to investigate the role of switching from cigarette smoking (CS) to tobacco heat system (THS) on the clinical outcome of closed tibia fractures from smokers' orthopedic patients. Validated and standardized assays, medical state and self-reported outcomes will be evaluated in orthopedic patients' smokers …

30 years of age All Phase N/A
N Nicolo Biavardi

Evaluation of STIMULAN Device and AI Model in Preventing Fracture Infections

This is a prospective, single-center, double-blind randomized clinical trial aimed at evaluating the efficacy and safety of the extended-release antibiotic device, STIMULAN, in preventing infections in patients with open fractures. The study will enroll 40 patients from IRCSS San Raffaele's Emergency Department and Orthopedics and Traumatology Unit. Patients will be …

- 65 years of age All Phase N/A
S Stacee Baker, BSN, RN

Pilon Fracture With Intra-articular Injection of N-Acetylcysteine (Pilon NAC)

High energy intra-articular fractures of the distal tibia, or Pilon fracture, is a devastating injury with multiple short and long term complications. The incidence of these injuries is increasing as survival rates after motor vehicle collisions increase. The current standard of care for high energy pilon fractures is to place …

18 years of age All Phase 4
a abdelkader hegazy, bachelor

Inter Flex Three Dimensional Plate in Management of Mandibular Fracture RCT

The goal of this clinical trial is to learn if The use of a 3D-designed Inter-flex plate will achieve safe and desirable anatomical \& functional restoration with reduced operative time in mandibular fracture, Improvement of occlusal and inter-cuspal relation in addition to stabilized intra-fragmentary mobility, Offer greatest resistance to displacement …

18 - 50 years of age All Phase N/A
K Kyrsten Butterfield, BSc

Static Helical Screw Locking of Pertrochanteric Femur Fractures Using the TFN-A

The study will investigate the shortening and collapse of pertrochanteric fractures following surgical management with the TFN-Advanced nailing system. The focus will be on comparing radiographic assessments of nails which have been statically locked versus dynamically locked. This is a randomized control study with the initial invention being randomized to …

18 years of age All Phase N/A
L Lizabeth Summerfiled

Does Joint Lavage Reduce Intraarticular Inflammation in High-energy Tibial Pilon Fractures?

High-energy tibial pilon fractures have historically been associated with poor outcomes largely due to the elevated risk of severe post-traumatic arthritis. Intraarticular fractures result in a pro-inflammatory hemarthrosis that may further exacerbate the chondral damage that was sustained due to the original injury. This project will study the effect of …

18 years of age All Phase N/A
A Ammar Ali Dr Ammar Ali, Bachelor in Dental surgery

Comparison of Submucosal Dexamethasone and Methylprednisolone in Postoperative Sequelae of Parasymphsis Fractures

The rationale of the current research is to address the limitation of existing knowledge as it is not clear which of the two drugs (Dexamethasone or Methylprednisolone) is more effective in reduction of postoperative sequelae in patient with mandibular parasymphysis fracture. This study fills the gap by providing sound evidence …

18 - 40 years of age All Phase 2

Home-Based Photobiomodulation Effects in the Postoperative Period of Distal Radius Fractures

This double-blind, randomized controlled clinical trial aims to evaluate the adjuvant effect of home-based photobiomodulation (PBM) therapy on the rehabilitation of surgically treated DRFs combined with an unsupervised home exercise program. A total of 42 participants will be randomly allocated into two groups. The Control Group will undergo the standard …

18 - 65 years of age All Phase N/A
J Jiawei Jiang, Dr

Percutaneous Vertebral-disc Plasty for Thoracolumbar Very Severe Osteoporotic Vertebral Compression Fractures

Purpose: To compare the clinical outcomes and radiological parameters of patients undergoing percutaneous vertebroplasty (PVP) versus those undergoing percutaneous vertebral-disc plasty (PVDP) for back pain, segmental instability, and kyphosis due to thoracolumbar very severe osteoporotic vertebral compression fractures (vsOVCFs). This prospective study included elderly patients with thoracolumbar vsOVCFs. All the …

58 - 84 years of age All Phase N/A

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