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Obesity Clinical Trials

A listing of Obesity medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,166 clinical trials
M Michael R Lowe, PhD

A Study to Investigate Why Overweight People Regain Weight After Losing Weight in a Behavioral Weight Loss Program

The goal of this clinical trial is to determine the physiological basis for the differences in weight regain among adults (25-59 years old) with obesity following participation in a behavioral weight loss program. Eligible participants will undergo a baseline evaluation after which they will enter an up to 20 week …

25 - 59 years of age All Phase N/A

Predictors of Behavioral Obesity Treatment Outcomes

Socioceconomically disadvantaged individuals typically have poor outcomes in behavioral weight loss interventions, but the reasons for this are unknown. This project will characterize the mechanisms through which adverse daily experiences and present bias -- a cognitive adaptation to harsh and unpredictable environments -- account for disparities in weight loss outcomes.

18 years of age All Phase N/A
C Claudia Dreyer, MS

Circadian Misalignment and Energy Balance

Preliminary findings from the investigators' lab suggest that circadian misalignment, occurring when meals and sleep are mistimed from one another, alters resting state neuronal processing in areas relevant to food reward and interoception; supporting a role of sleep and meal misalignment, on energy balance regulation. No study has been done …

20 - 49 years of age All Phase N/A

Inspiratory Muscle Strength Training in Adults With Obesity

The purpose of this study is to determine whether inspiratory muscle strength training reduces blood pressure in adults with obesity.

20 - 45 years of age All Phase N/A
R Rachel Price, MPH

Project SHINE (Sleep Health INitiative for Equity): Culturally Informing a Sleep Extension Intervention for African American Adults

The proposed research aims to reduce obesity-related health disparities by promoting healthy lifestyle behaviors among African Americans (AAs), given the high disease burdens associated with low physical activity, insufficient sleep, and obesity. There will be two phases to the proposed research. Phase 1 (Aim 1) will encompass formative research and …

21 - 75 years of age All Phase 1/2
I Ivo Boskoski, MD, PhD

The ESG Integrity Study: Effect of Proton Pump Inhibitors on the Structural Integrity of Endoscopic Sleeve Gastroplasty

The study is a single center randomized, open-label, phase IV clinical trial. Obese patients who have indication to Endoscopic sleeve gastroplasty (ESG) for clinical reasons are included and ESG is performed as per clinical practice. After randomization, the patients are divided in two arms: Arm A: patients will stop proton …

18 - 65 years of age All Phase 4
C Christian Roux

Effect of Agonist GLP1 on Adipose Tissue in Patients Undergoing Bariatric Surgery

Normalizing weight gain and preventing the redistribution of body fat is a major health issue, and could help prevent the onset of various symptoms of metabolic syndrome. Above all, it is important to understand the mechanisms by which these different treatments affect adipose tissue. To this end, the investigators will …

18 years of age All Phase N/A
S Shifen Xu, PhD

Effect of Acupoint Thread Embedding on Obesity

The investigators describe a protocol for a randomized controlled trial to find out the effect and safety of acupoint thread embedding on losing weight in obese patients.

18 - 45 years of age Female Phase N/A

Laparoscopic Ileal Interposition and Weight Regain

The investigators will study the Ileal interposition to the treatment of weight regain after Roux-en-Y gastric bypass, assessing weight loss, body composition, quality of life, metabolic biomarkers, inflammatory biomarkers, and incretin hormones

21 - 60 years of age All Phase N/A
A Alexander N Prezioso, MD

First in Human Study in Subjects With Obesity, But Otherwise Healthy

This is a First in Human study to evaluate the safety and tolerability of DA-1726 following single and multiple doses in participants with obesity, but otherwise healthy subjects.

18 - 65 years of age All Phase 1

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