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Obesity Clinical Trials

A listing of Obesity medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,166 clinical trials
C Cagri Delibay

Executive Function in Obese

This study was planned to examine the effect of executive function problems on physical performance and general well-being in obese individuals.

18 - 65 years of age All Phase N/A
A Ann De Bruyne

Pharmacokinetics and Pharmacodynamics of Intravenous Paracetamol in Morbidly Obese and Non- Obese Patients.

Obese patients may need higher doses of acetaminophen (APAP) for adequate analgesia, due to increased total clearance and distribution volume. APAP-induced hepatotoxicity is mainly caused through CYP2E1 pathway. Its activity is induced by obesity, potentially endangering the safety profile of APAP. Metabolic-dysfunction associated liver disease (MASLD) is an important associated …

18 - 70 years of age All Phase N/A
A Alessandro Sartorio, MD

Metacognitive Beliefs in Obese Patients

The study aims to investigate the presence of metacognitive beliefs, emotional regulation, and emotional eating in obese patients and their possible relationships.

18 - 65 years of age All Phase N/A

Adrenergic Cholinergic Enteric Measures/Mapping

Patients seen who had autonomic and enteric profiling (Adrenergic, Cholinergic, Enteric Measures/Mapping=ACEM_ from 2012-2019 at the University of Louisville.

10 - 80 years of age All Phase N/A
Y Yenny Leal

Inter-relationships Among Glucose, Brain, Gut Microbiota and MicroRNAs (IRONmiRNA).

The brain is a recognized target of iron deposition. This process is enhanced by the presence of obesity and hyperglycemia and impacts cognitive functions. There is evidence suggesting that the gut microbiota composition modulates this process. It has been proposed that microRNAs are mediators in the dialogue between the composition …

30 - 65 years of age All Phase N/A
S Salvatore F. Vadalà di Prampero, MD, Phd

Bariatric Endoscopy for Treatment of Obesity

A single-center, randomized controlled study will be conducted in order to compare three Endoscopic Gastroplasty (EG) techniques with a control group of obese patients (BMI 30-44.99 kg/m2) at Gastroenterology and Gastrointestinal Endoscopy Unit, Mater Olbia Hospital, Qatar Foundation Endowment & Gemelli Foundation, Italy in period June 2020 - June 2023, …

18 - 70 years of age All Phase N/A
H Hany Eldhahaby, MD

Evaluation of Sagittal Abdominal Diameter as a Predictor of the Skin to Epidural Space Distance in Obese Patients

The aim of this study is to evaluate the use of the sagittal abdominal diameter (SAD) as a potential predictor of the skin to epidural space distance (SESD) and to compare its accuracy versus that of the BMI as a previously validated predictor

18 years of age All Phase N/A
L Luisa Gilardini, MD

Abnormal Eating and Taste Perception in Subjects With Obesity

The identification of safe and effective strategies for weight loss and long-term maintenance is critical to reduce the alarming prevalence of obesity worldwide and mitigate obesity-associated health risks. Specifically, Binge Eating (BE) and Food Addiction (FA) behaviors are well known causes of failed weight loss and weight regain. The definitions …

18 - 60 years of age All Phase N/A
J Julie Sorg, MSN

Brown Adipose Tissue Activity in Response to Semaglutide Administered to Obese Subjects.

Glucagon like peptide (GLP-1) agonists, such as liraglutide, exenatide, and semaglutide, have been increasingly used as a medication to address the current twin epidemics of diabetes and obesity. Their activities include increasing insulin production by pancreatic beta cells, improving insulin sensitivity in muscles and weight loss. The mechanisms underpinning the …

18 years of age All Phase N/A
Y Yenny Leal

Involvement of the Gut Microbiota-brain Cross-talk in the Loss of Eating Control

Overweight and obesity are increasingly prevalent worldwide. These bodyweight disorders are closely related to deficiencies in the control of food intake. A potential yet unexplored mechanism to explain the loss of eating control is the interaction between the gut microbiota and the brain. The mechanisms underlying the communication between the …

30 - 65 years of age All Phase N/A

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