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depression Clinical Trials

A listing of depression medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,259 clinical trials
M Markus Björnström

A Metacognitive Group Therapy of Depression and Anxiety in Youth With Autism

The goal of this open clinical trial is to try out and evaluate a group metacognitive treatment protocol, for adolescents aged 15-18 years of age with anxiety and/or depression and an autism diagnosis. The main questions it aims to answer are: How does the recruitment to the study work and …

15 - 18 years of age All Phase N/A
D David Edelman, MD MHS

A New Intervention to Improve Function in Veterans With Anxiety and Depression

Anxiety and depression symptoms occur at high rates in Veteran populations and can significantly impact function, compromising the ability to work and to successfully form and maintain valued relationships. Several other symptoms commonly occur with anxiety and depression, including poor sleep quality and chronic pain. Since all these symptoms frequently …

18 - 65 years of age All Phase 2
M Mohamed Mamdouh Elsayed, MD

Effect of Intradialytic Exercise on Sleep, Depression and Anxiety in HD Patients

this study aims To assess the effect of intradialytic exercise program on sleep quality, depression and anxiety in HD Patients.

18 years of age All Phase N/A

IMAGINE: Pilot Trial of a Digital Group Intervention to Prevent Perinatal Depression

The goal of this clinical trial is to evaluate if a digital group intervention (named IMAGINE) can prevent depression in perinatal populations. The main questions it aims to answer are: Does IMAGINE engage cognitive behavioral therapy targets? Does IMAGINE lead to lower depression scores? Is IMAGINE acceptable, appropriate, usable and …

16 years of age Female Phase N/A
R Romain COLLE, MD - PHD

Early Effects of Ketamine vs Placebo With Venlafaxine in Severe Depression Patients

Unipolar major depressive disorder is the leading cause of disability worldwide. The most commonly used treatments for major depressive episodes (MDE) are antidepressant medications. However, they have limited efficacy and their onset of action is long, ranging between 2 to 6 weeks. During this period, hospitalization can become necessary, especially …

18 - 65 years of age All Phase 3
T Temesgen Mekonnen

Salutogenesis and Self-efficacy-based Childbirth Education Programme for Preventing Postpartum Depression

Although the transition to motherhood is often a joyful experience, there is evidence that teenage motherhood can present many stressful challenges, potentially leading to the development of postpartum depression. Postpartum depression (PPD) remains a public health issue with negative consequences for both mothers and their babies. The aim of this …

13 - 19 years of age Female Phase N/A
A Alexandra Anderson, BS

Ketamine Pharmacokinetics and Pharmacodynamics for Postpartum Depression and Pain After Cesarean Delivery

The purpose of this study is to identify pharmacokinetics of postpartum ketamine infusion. This study will assess ketamine kinetics and metabolism in this setting. Ketamine is expected to exert different kinetics during the physiologic state of post-pregnancy. The goal in conducting this study is to better understand the pharmacokinetics and …

18 years of age All Phase 1
D Dan Zhang

An ISO Principle-Based Music Intervention for Reducing Stress, Anxiety, and Depression

This study aims to evaluate the effectiveness of a music-based intervention, guided by the ISO principle, in reducing stress, anxiety and depression induced by work, family or others among adults. The ISO principle suggests that emotional regulation can be supported by gradually modifying the emotional characteristics of music to help …

20 - 45 years of age All Phase N/A
H Hu ShaoHua

Efficacy and Safety Assessment of Temporal Interference Stimulation to Improve Bipolar Depression

The aim of this study was to explore the efficacy and safety of temporal interference stimulation to improve bipolar depression, as well as to explore the corresponding neuroimaging mechanisms using magnetic resonance and electroencephalogram to provide novel intervention protocols and objective indicators of efficacy prediction for depressive episodes in bipolar …

18 - 45 years of age All Phase N/A
R Riccardo Bortoletto, MD

The Supplementation Therapy in Autism and Response to Treatment Study

In addition to the "core" symptoms of ASD (i.e., impaired communication, impaired reciprocal social interaction and restricted, repetitive and stereotyped patterns of behaviors or interests), it is estimated that up to 70% of autistic people present at least one comorbid psychiatric disorder, leading to a deterioration in quality of life, …

18 - 35 years of age All Phase N/A

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