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depression Clinical Trials

A listing of depression medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,259 clinical trials
A Alina Wilkowska, MD, PhD

M3VAS Validation in Polish Population

Low mood and anhedonia represent the fundamental symptoms of major depressive disorder (MDD). Nevertheless, there is currently no standardized visual analogue scale available to assess the extent of both symptoms concurrently. The Maudsley 3-item Visual Analogue Scale (M3VAS) is a newly developed tool for participants to self-assess core symptoms of …

18 years of age All Phase N/A

Brain Imaging Biomarkers of Pathological Brain Aging in Late-life Depression

This study investigates the relationships and differences in PET-MRI brain imaging biomarkers of abnormal aging and behavioral measures in late life depression compared to healthy controls, and evaluates relationships and differences in the same imaging and behavioral measures following electroconvulsive therapy. The study tests the hypotheses that late-life depression will …

60 years of age All Phase N/A

Latino Teen Depression Treatment Study

Despite experiencing higher rates of depressive symptoms (Center for Disease Control and Prevention, 2020) and similar rates of Major Depressive Disorder (MDD; Substance Abuse and Mental Health Services Administration (SAMHSA), 2019), Latino adolescents in the U.S. are significantly less likely than their non-Latino White peers to receive treatment for MDD …

13 years of age All Phase N/A
D David Crowley

Early Life Stress and Depression: Molecular and Functional Imaging

Severe childhood adversity accounts for a large portion of psychiatric illness, and an increased risk for major depressive disorder (MDD). For some individuals, childhood adversity has negative psychological and medical consequences; others preserve mental and physical health despite such experiences (they are resilient). In spite of this, little is known …

20 - 32 years of age Female Phase N/A
K Katharine Dunlop, PhD

Effect of Suicidality on Social Cognition

Major Depressive Disorder (MDD) is a very common illness that is usually treated with antidepressant medication. Depression can be caused by many things such as childhood experiences, genetics, and changes in the way the body and brain function. It is most likely caused by a combination of several of these …

18 - 65 years of age All Phase N/A

The Neurobiological Fundaments of Depression and Its Relief Through Neurostimulation Treatments

The study will apply state of the art radiology through advanced magnetic resonance imaging (MRI) techniques to investigate structural and functional brain effects of electroconvulsive therapy (ECT) and repetitive transcranial magnetic stimulation (rTMS).

18 years of age All Phase N/A
C Chai Nien Foo

Biomarkers, TCM Body Constitution, Dietary Pattern and Psychological Factors in Predicting Depression

This study aims to determine the predictors of depression among university students in Universiti Tunku Abdul Rahman (UTAR) Sungai Long Campus.

18 - 30 years of age All Phase N/A
K Katie Tucker

FMRI Accelerated TMS Depression

This study aims to investigate whether phenotypic-related brain states revealed by a novel INSCAPE ("Individualized Network-based Single-frame Coactivation Pattern Estimation") neuroimaging method in Major Depressive Disorder (MDD) patients can track brain recovery of MDD patients over an accelerated antidepressant transcranial magnetic stimulation (TMS) treatment.

18 - 65 years of age All Phase N/A
C Caitlin Holley, Ph.D.

Veteran's Perceptions of Ketamine-Assisted Psychotherapy for Depression and End-of-Life

The goal of this exploratory, mixed-method design study is to gather qualitative and quantitative data obtained through interviews and questionnaires with veterans who are currently enrolled at the VA for healthcare. The main question this study aims to answer is: How do veterans aged 65+ who are enrolled for care …

65 years of age All Phase N/A

Characterizing Cognitive Decline in Late Life Depression: The ADNI Depression Project

The purpose of this research study is to characterize the mechanisms contributing to cognitive impairment and accelerated cognitive decline in Late Life Depression (LLD). This is a non-randomized, observational, non-treatment study that originally launched in 2015, enrolling 133 participants. From the originally enrolled participants, the continuation of the ADNI-D study …

65 years of age All Phase N/A

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