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depression Clinical Trials

A listing of depression medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,259 clinical trials
P Pernille Hegre Sørensen

Acute Efficacy and 6 Months Follow up After Electroconvulsive Therapy

The overall aim of the current project is to assess the acute and long term outcome of ECT (both patient and clinician rated) in a non-selected patient cohort from ordinary clinical activity, and to seek out factors predicting response and remission, side effects and relapse.

18 years of age All Phase N/A
E Elizabeth Ballard, Ph.D.

Long-term Observation of Participants With Mood Disorders

Background More than 12,000 people have taken part in research at the Experimental Therapeutics & Pathophysiology Branch at the National Institute of Mental Health Intramural Program. This has led to advances in the treatment of depression, bipolar disorder, and suicide risk. Researchers want to follow up with this group to …

18 - 99 years of age All Phase N/A
M Matthew Maple

Cognitive and Affective Processes Online

This study will provide data for evaluating the psychometric characteristics of the tests assessing cognitive flexibility, including their (1) internal consistency, (2) feasibility and tolerability, their (3) convergent and discriminant validity of cognitive and affective constructs such as those introduced to understand mental disorders, and (4) sensitivity (and correspondence) to …

18 years of age All Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Characterization and Treatment of Adolescent Depression

This research study seeks to find causes and treatments of depression in teenagers. The study goals are to increase our knowledge of treatments for depression and understand how the brain changes when teenagers have depression. The study will also compare teenagers with depression to those without mental health diagnoses. This …

11 - 25 years of age All Phase N/A

Retrospective Analyses of the Greenbrook Database Evaluating Mental Health Treatments

The study involves multiple retrospective analyses to understand the utilization of mental health treatments provided at Greenbrook and their effectiveness

5 - 100 years of age All Phase N/A
H Hu ShaoHua

AI-based Multi-center Research on Identification/Classification/Aided Diagnosis of Mood Disorder

At present, diagnosis and recognition of depression and bipolar disorder are mainly based on subjective evidence such as clinical interview and scale evaluation. The corresponding diagnosis basis has some shortcomings, such as poor diagnostic reliability and failure in early identification of bipolar disorder. Therefore, it is of great significance to …

15 - 55 years of age All Phase N/A
K Kari M Kristiansen, MSc

Quality Register for Geriatric Psychiatry

QualGeP (KVALAP) is a quality register in Viken Research network for Geriatric Psychiatry. The objectives of the register are to enhance our knowledge of old persons with severe psychiatric disorders, and to secure an optimal medical evaluation, treatment and care for these patients. The data in the register will be …

65 years of age All Phase N/A
S Sangita Sethuram, MBA, CCRP

Dallas 2K: A Natural History Study of Depression

The primary objective of this initiative is to implement a prospective study that will allow us to identify and validate biosignatures of response to treatments for depression and depression outcome (using an integrated array of participant specific data: socio-demographic, lifestyle, clinical and behavioral assessments, fluid-based biomarkers, genomics, neuroimaging, EEG, and …

10 years of age All Phase N/A
D Dr. Kolby Walker

Kintsugi Voice Device Pivotal Study

A prospective, single arm, non-randomized, pivotal clinical validation study to evaluate the ability of the Kintsugi Voice Device (the Device) to aid clinical assessment for depression by comparing its output with a diagnosis made by a clinician using the Structured Clinical Interview for DSM-5 (SCID-5-RV) for up to 1000 English …

22 years of age All Phase N/A

The Rapid Diagnosis of MCI and Depression in Patients Ages 60 and Over

Mild cognitive impairment (MCI) leading to Alzheimer's disease and related disorders (ADRD) represents a significant health and economic burden of the rapidly expanding senior population. The accurate detection and diagnosis of MCI and its common comorbidity, late-life depression (LLD), is essential for prolonging patient quality of life and developing advancements …

60 years of age All Phase N/A

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