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Nephropathy Clinical Trials

A listing of Nephropathy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 338 clinical trials
D David SC Hui, MD

To Assess the Management of Patients on Global Initiative of Asthma (GINA) Step 4 and 5 Treatment in Hong Kong

This study aims to prospectively assess the asthma control and management of asthma patients who are on step 4, 5 asthma of GINA in Hong Kong (on at least medium-dose ICS-LABA as controller therapy for asthma) and also observe their exacerbations over 2 years. In addition, this study will also …

18 years of age All Phase N/A
J Jane Sachs, MBE, MPH

Microglia Activation in Asthma

The primary purpose of this study is to provide preliminary data to determine if an acute increase in airway inflammation, provoked by an inhaled allergen challenge, is associated with an increase in microglial activation and may inform whether individuals with asthma, in the long-term, are at increased risk for neurodegeneration, …

18 - 50 years of age All Phase N/A
T Thomas J Bahmer, MD

Adult Arm of DZL All Age Asthma Cohort (ALLIANCE)

Deep Phenotyping of adult asthma patients: severity from mild to severe both atopic and non-atopic both childhood and adult onset both smokers and non-smokers corresponding pediatric cohort (Pediatric Arm of DZL All Age Asthma Cohort) with equivalent SOPs regarding collection of biomaterial and clinical data incl. lung function, further processing …

18 - 99 years of age All Phase N/A
V Virginie NIEL

Effect of Benralizumab on Airway Remodeling in Asthma

The anti-interleukin (IL)-5 receptor benralizumab inhibits eosinophilic inflammation but its potential effect on airway remodeling remains unknown. The main objective of this study is to assess the effect of benralizumab in an in vitro model of airway remodeling using cells obtained from asthmatic patients.

18 years of age All Phase N/A
K Katie Mills

Finding Correlations Between Asthma Exacerbation, Physiological Measurements and Environmental Factors

To identify asthma-related physiological changes observed by wearable devices in real-world conditions by monitor multiple sensing modalities (e.g., heart rate (HR), heart rate variability (HRV), activity level, spirometry, coughing sounds) in order to find reliable signatures of impending asthma exacerbation and systematically explore any challenges on the use of wearable …

14 - 18 years of age All Phase N/A
D David SC Hui, MD

Relationship of Airway Microbiota, Endotype and Phenotype in Adult Asthma

Increasing evidence supports that the respiratory microbiota, including viral and bacterial microorganisms, play important roles in respiratory health and disease. Microbial patterns in airways may induce distinctive endotypes of asthma. Previous studies suggest host-microbiota interactions in children may account for the heterogeneity of endotypes and clinical presentations. However, information on …

18 years of age All Phase N/A
C Clinical Trials Manager

Spirometric Response to Bronchial Thermoplasty in Patients With Severe Asthma

The investigators hypothesis is that there will be improvement in FEV1 in patients with severe asthma. This is a retrospective data study that reviews preexisting medical records; no patients will be enrolled.

18 - 99 years of age All Phase N/A

The Cohort Study for Asthma in China

The study is to establish a standardized asthma cohort study, build an information network platform system and a biospecimen bank for asthma cohort, establish clear follow-up standards and norms, observe the asthma outcomes and identify biomarkers to predict asthma outcomes.

18 years of age All Phase N/A

Mechanism(s)of Airflow Limitation in Moderate-severe Persistent Asthma

The purpose of this study is to evaluate the site and mechanisms responsible for expiratory airflow limitation in chronic, treated, non-smoking, stable asthmatics with moderate to severe persistent expiratory airflow obstruction. Treatment will include inhaled corticosteroids and long acting beta2agonists and long acting muscarinic antagonists. We are interested in determining …

10 - 95 years of age All Phase N/A

Fasenra Pediatric Japan Post-Marketing Study(PMS)

The purpose of the investigation is to confirm the followings under the post-marketing actual use of Fasenra® Subcutaneous Injection 30 mg / 10mg Syringe (hereinafter referred to as Fasenra). Development of unexpected related AEs* To grasp development of related AEs* in the real-world post-marketing setting. Effectiveness (pulmonary function and asthma …

years of age All Phase N/A

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