Overview
This study compares measurements of body composition to outcomes of breast reconstruction.
Description
PRIMARY OBJECTIVES:
1\. Determine feasibility of collecting measurements of body composition.
SECONDARY OBJECTIVES:
- Define the differences in body composition between participants undergoing breast reconstruction who develop complications and those who do not.
- To determine the implications of different measures of body composition on outcomes of breast reconstruction.
- Compare utility of body composition measurements versus other anthropometric assessments on assessing risk of complications following breast surgery.
OUTLINE: This is a observational study. Participants are assigned to 1 of 2 cohorts and will be follow-up for up to 2 years.
Eligibility
Inclusion Criteria:
- Patients must have histologically confirmed breast malignancy or increased risk of developing a breast malignancy.
- Age ≥ 18 years.
- Scheduled to undergo mastectomy with immediate breast reconstruction using a permanent implant, tissue expander, or autologous tissue (e.g. Deep Inferior Epigastric Perforator (DIEP) flap, muscle-sparing Transverse Rectus Abdominis Myocutaneous (msTRAM) flap, Profunda Artery Perforator (PAP) flap).
- Ability to understand a written informed consent document, and the willingness to sign it.
Exclusion Criteria:
- Any significant medical condition or laboratory abnormalities, which places the subject at unacceptable risk if he/she were to participate in the study.
- Pregnant or breastfeeding.
- Patients assigned male at birth.
- Non-cisgender women.
- Patients with implanted electronic medical devices (e.g. pacemaker, defibrillator).
- Patients with prosthetic limbs.