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Study to Determine the Antitumor Activity of New CAR-macrophages in Breast Cancer Patients' Derived Organoids

Study to Determine the Antitumor Activity of New CAR-macrophages in Breast Cancer Patients' Derived Organoids

Recruiting
18 years and older
All
Phase N/A
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Overview

Cell-based immune therapy using modified macrophages is a promising therapeutic approach in breast cancer. The objective of this cohort study is to collect tumor samples to develop patients' derived organoids to test the antitumor activity of newly developed CAR-macrophages. Other biological samples will be collected such as blood to analyze the host inflammatory status.

Eligibility

Inclusion Criteria:

  • Male or female aged 18 years or more
  • Histologically confirmed breast cancer at any stage
  • Requiring surgery or tumor biopsy as standard of care
  • Any or no systemic treatment
  • Signed informaed consent
  • Health insurance coverage

Exclusion Criteria:

  • Opposed to biospecimen collection

Study details
    Breast Cancer

NCT05007379

Centre Oscar Lambret

13 May 2026

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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