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Randomized Clinical Trial for Predictors of Successful Extubation of Pediatric Patients From Mechanical Ventilation Either on High Velocity Nasal Insufflation or Simple Nasal Oxygen and Comparing the Outcome

Randomized Clinical Trial for Predictors of Successful Extubation of Pediatric Patients From Mechanical Ventilation Either on High Velocity Nasal Insufflation or Simple Nasal Oxygen and Comparing the Outcome

Recruiting
2-13 years
All
Phase N/A

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Overview

A randomized clinical trial about predictors of successful extubation of pediatric patients from mechanical ventilation either on High Velocity Nasal Insufflation or simple nasal oxygen and comparing the outcome

Description

A randomized clinical study is comparing between extubation on High Velocity Nasal Insufflation or simple nasal Oxygen ensuring that all patients had successful weaning predictors before extubation and comparing the outcome whether patient needed upgrading of oxygen support or reintubation within 48 hours, presence of respiratory distress or stridor post extubation, knowing mechanical ventilaton free days after extubation, time of complete weaning of oxygen support to room air and also morbidity and mortality.

Eligibility

Inclusion Criteria:

  • Age between 2 months and 13 years old with minimum weight 4kg
  • Both sexes
  • Patients on mechanical ventilation for at least 24 hours for any indication

Exclusion Criteria:

  • Patients not ready for weaning from mechanical ventilation
  • Contraindications to use of High velocity nasal insufflation
  • Prolonged mechanical ventilation for more than 21 days

Study details
    Comparing the Outcome Between High Velocity Nasal Insufflation and Simple Oxygen After Successful Weaning From Mechanical Ventilation

NCT07383051

Cairo University

26 February 2026

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