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Hemorrhoid Suture Mucopexy Combined With Laser Hemorrhoidoplasty

Hemorrhoid Suture Mucopexy Combined With Laser Hemorrhoidoplasty

Recruiting
18 years and older
All
Phase N/A

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Overview

This prospective cohort study evaluates whether combining "suture mucopexy" (a simple stitch-based lift of prolapsed tissue) with Laser Hemorrhoidoplasty (LHP) can effectively relieve pain, bleeding and prolapse in adults with moderate-to-severe hemorrhoids (Grades II-IV). Participants will undergo the combined, non-Doppler-guided procedure and be followed for one year. The primary question is how long patients need post-operative pain medication and if they first experience complete symptom relief; secondary questions examine quality-of-life, safety (bleeding, urinary retention, stenosis) and the rate of hemorrhoid recurrence/re-operation.

Description

Laser Hemorrhoidoplasty (LHP) offers a minimally invasive option for symptomatic hemorrhoids, yet in advanced disease (Goligher III/IV) recurrence rates of 20-35 % have been reported because residual mucosal prolapse persists. Adding a suture-based mucopexy (SM) eliminates the prolapse and ligates feeding vessels without the need for Doppler guidance, thereby potentially reducing recurrence while preserving the low-pain advantage of LHP. Preliminary experience with 50 patients at this centre demonstrated feasibility, low early complication rates, and promising symptom control, justifying a formal prospective evaluation.

The present study is a single-center, prospective observational cohort enrolling consecutive eligible adults over a 24-month accrual period. All participants receive the same combined LHP + SM technique; no comparator arm is planned. Follow-up visits occur at postoperative week 6, month 6 and month 12.

Eligibility

Inclusion Criteria:

  • Adults (\>18 years).
  • Symptomatic Hemorrhoidal Disease (Goligher Grades II, III, IV).
  • Patients with or without recurrent disease after prior procedures (e.g., RBL, infrared coagulation, Milligan-Morgan, etc).

Exclusion Criteria:

  • Acutely thrombosed hemorrhoids.
  • Concomitant anal fistula or abscess requiring separate surgical management.
  • IBD (Crohn's/Ulcerative Colitis) with active rectal involvement.
  • Previous Stapled Haemorrhoidopexy (SH/Longo).

Study details
    Haemorrhoid
    Haemorrhoidal Bleeding
    Anorectal Surgeries
    Anorectal Diseases

NCT07404774

National and Kapodistrian University of Athens

26 February 2026

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