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At-Home Neuromodulation for Female Sexual Dysfunction

At-Home Neuromodulation for Female Sexual Dysfunction

Recruiting
18-85 years
Female
Phase N/A

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Overview

This pilot study investigates the regular use of non-invasive dorsal genital nerve stimulation (DGS) for the treatment of female sexual dysfunction (FSD). The researchers aim to determine whether subjects with FSD can correctly follow an at-home treatment regimen and to demonstrate that DGS can improve FSD arousal symptoms in premenopausal and postmenopausal women. Some subjects will use a smart vibrator for comparison to DGS.

Eligibility

Inclusion Criteria:

  • Capable of speaking and understanding English.
  • Able to comprehend the clinical study procedures and provide informed consent.
  • Identified as having female sexual dysfunction with a Female Sexual Function Index (FSFI) score of 26.55 or less and a score of 3 or less on one or more of the FSFI subdomains of lubrication, arousal, and orgasm.
  • Willing and able to adhere to the study protocol
  • Able to attend experimental sessions at Michigan Medicine at both the start and conclusion of the study.

Exclusion Criteria:

  • Not currently sexually active.
  • Pregnant or planning to get pregnant during the study period.
  • History of a neurological disorder or impairments affecting pelvic organ function, including diagnosed with dorsal genital nerve damage, lower motor dysfunction, or other related conditions.
  • Implanted with a neurostimulator for bladder or bowel function.
  • Have a skin condition that would predispose them to sensitivity to the stimulation electrodes.
  • Female sexual dysfunction limited solely to low desire, without issues in lubrication, arousal, or orgasm.
  • Clinically diagnosed bladder dysfunction, pelvic pain, or other pelvic organ symptoms; or a score of 8 or higher on the American Urological Association Symptom Index (AUASI).
  • Unable or unwilling to adhere to the study protocol
  • Simultaneously participating in another research study that may affect the results of this study.

Study details
    Female Sexual Dysfunction

NCT06932302

University of Michigan

1 February 2026

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