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Atrial Strain in Septic Shock

Atrial Strain in Septic Shock

Recruiting
18 years and older
All
Phase N/A

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Overview

Septic shock is a critical condition associated with high mortality. Transthoracic echocardiography is widely used to evaluate cardiac function and guide treatment. Left and right atrial strain (LAS and RAS) measured via speckle tracking echocardiography have shown prognostic value in cardiovascular diseases. However, differences exist between echocardiographic software, leading to challenges in result comparability. This study aims to compare LAS and RAS measurements between ECHOPAC and UWS software, evaluate AutoStrain technology, and assess reproducibility across observers. The study is non-interventional and will use retrospective echocardiographic data from patients treated for septic shock. The findings will contribute to improving measurement standardization in critically ill patients.

Eligibility

Inclusion Criteria:

  • Age: \>18 years
  • Adult patients admitted to critical care for septic shock (SEPSIS-3 definition)
  • TTE performed as part of medical management
  • No objection to data usage

Exclusion Criteria:

  • Pregnancy
  • Moderate to severe valvular regurgitation/stenosis (\>grade 2)
  • Ventricular or supraventricular tachyarrhythmia (HR \>140 bpm) at the time of TTE
  • Poor echogenicity preventing LAS measurement
  • Mechanical circulatory support
  • Pacemaker dependence
  • Patients under guardianship

Study details
    Septic Shock
    Left Atrial Strain
    Right Atrial Strain
    Transthoracic Echocardiography
    Speckle Tracking
    Echocardiographic Software
    Reproducibility
    Critical Care

NCT06832436

Centre Hospitalier Universitaire, Amiens

1 February 2026

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