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Ketorolac Effects on Post-operative Pain and Lumbar Fusion

Ketorolac Effects on Post-operative Pain and Lumbar Fusion

Recruiting
18-85 years
All
Phase 4

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Overview

A double blind prospective randomized trial of IV ketorolac vs. placebo in management of patients undergoing lumbar one or two level spinal fusions.

Eligibility

Inclusion Criteria:

  • 18-85 years old (inclusive)
  • Elective posterior lumbar instrumented fusion
  • One or two level fusion
  • Consent to participate in study and willing to adhere to study follow up
  • English proficiency

Exclusion Criteria:

  • \< 18 or \> 85 years old
  • History of renal failure, dialysis, or creatinine over 1.50 mg/dl
  • Active or recent smoker (active within past 6 months)
  • Revision surgery
  • Auto/worker compensation
  • Active cancer or history of chemotherapy in past 6 months
  • Active narcotic use within 3 months of surgery date
  • Infection at operative levels
  • Any allergies to NSAIDs or Opioids

Study details
    Lumbar Spinal Fusion

NCT06513208

University of Maryland St. Joseph Medical Center

1 February 2026

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