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Effect of Patient-Controlled Transcutaneous Electrical Acupoint Stimulation on Quality of Life in Chronic Cancer Pain

Effect of Patient-Controlled Transcutaneous Electrical Acupoint Stimulation on Quality of Life in Chronic Cancer Pain

Recruiting
18-80 years
All
Phase N/A

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Overview

This study aims to objectively evaluate the effect of Patient-Controlled Transcutaneous Electrical Acupoint Stimulation (PC-TEAS) on improving the quality of life in patients with chronic cancer pain, thereby providing evidence-based medical support for its efficacy and offering practical basis for patients to achieve home-based auxiliary treatment based on their own needs. Furthermore, by observing and comparing changes in indicators such as pain-related scores, analgesic consumption, emotional scores, spontaneous bowel movements, and adverse events, this research will comprehensively assess the advantages of PC-TEAS in the management of chronic cancer pain and explore other potential benefits of this intervention for patients.

Eligibility

Inclusion Criteria:

  • Age between 18 and 80 years, regardless of gender;
  • Diagnosis of primary or metastatic malignant tumor confirmed by histopathology and/or cytology, consistent with the American Cancer Society criteria for malignancy;
  • Presence of cancer-related pain, defined as an average Numeric Rating Scale (NRS) score ≥ 2 over the preceding week or current regular use of opioid analgesics;
  • Life expectancy ≥ 3 months;
  • Eastern Cooperative Oncology Group Performance Status (ECOG-PS) score ≤ 2, stable vital signs, clear consciousness, intact pain perception, unimpaired communication, ability to cooperate with study procedures and complete assessments;
  • Provision of signed informed consent by the patient or their legal guardian after comprehensive explanation of the study;

Exclusion Criteria:

  • Pain not attributable to cancer;
  • Severe cardiopulmonary dysfunction or respiratory depression;
  • Implantation of cardiac pacemaker or metallic implants at stimulation sites;
  • Local skin lesions or conditions unsuitable for TEAS at the acupoint sites;
  • Severe psychiatric disorders or significant cognitive impairment;
  • Concurrent participation in other clinical trials that may interfere with the outcome evaluation of this study;
  • Previous history of transcutaneous electrical acupoint stimulation (TEAS) or transcutaneous electrical nerve stimulation (TENS);

Study details
    Quality of Life
    Chronic Cancer Pain

NCT07308951

The Third Affiliated hospital of Zhejiang Chinese Medical University

1 February 2026

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