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Impact of Breast Milk on the Infectivity and Transmission of Different Viruses "BREASTMILKVIR"

Impact of Breast Milk on the Infectivity and Transmission of Different Viruses "BREASTMILKVIR"

Recruiting
18 years and older
Female
Phase N/A

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Overview

Exclusive breastfeeding during the first six months of life and continued breastfeeding for at least 24 months constitute the optimal feeding method for infants and young children.

However, breast milk and breastfeeding can be significant pathways for the transmission of certain viruses.

The objective of this study is to examine the influence of human breast milk and its composition on viral infectivity and viral transmission of the HTLV-1 virus and arboviruses such as Zika virus, yellow fever, dengue, and tick-borne encephalitis.

Description

Exclusive breastfeeding during the first six months of life and continued breastfeeding for at least 24 months constitute the optimal feeding method for infants and young children.

However, breast milk and breastfeeding can be significant pathways for the transmission of at least three human viruses: HTLV-1, HIV, and human cytomegalovirus (CMV).

To address the following main objective: to study the influence of human breast milk and its composition on viral infectivity and viral transmission of the HTLV-1 virus and arboviruses such as Zika virus, yellow fever, dengue, and tick-borne encephalitis.The study plans to collect milk samples from lactating women who are registered with the Lactarium of Île-de-France to donate their breast milk.

Eligibility

Inclusion Criteria:

  • Age \> 18 years
  • Female gender
  • Lactarium Ile-de-France donors
  • Subjects covered by a Social Security scheme, excluding State Medical Aid

No inclusion criteria:

\- Women opposing participation in the study

Exclusion Criteria:

\- Positive HIV, HBV, HCV and HTLV serologies (Lactarium exclusion criteria)

Study details
    Breastmilk Collection

NCT06738563

Institut Pasteur

1 February 2026

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