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Adrenaline V/s Dopamine in Fuid Refractory Septic Shock

Adrenaline V/s Dopamine in Fuid Refractory Septic Shock

Recruiting
1-12 years
All
Phase N/A

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Overview

This study compares the efficacy of two drugs i.e Adrenaline and dopamine in fluid refractory type of septic shock which is a dreadful medical condition especially in children. The efficacy will be checked based on heart rate , GCS, capillary refill time , palpable pripheral pulse , urine output and systolic blood pressure.

Description

This is a randomized control trial in which children / patients diagnosed with Fluid refractory Septic shock will be provided with one of the two drugs ina randomzied way and their efficacy will be assesed on the basis of correction of various parameters at various points of time.

Eligibility

Inclusion Criteria:

Patients of both Genders having age range between 1month and 12 years with diagnosis of fluid refractory septic shock as per operational definition.

\-

Exclusion Criteria:

  • Patients with
    1. cardiopumonary Bypass during last 5 days
    2. Chronic Systemic disease like Chronic kidney Disease , cerebral palsy, congenital heart disease
    3. neuromuscular discorder
    4. Metabolic disorders
    5. Those who already had treatment at periphery for hypovolemia without any record of medication or sequential organ failure at presentation

Study details
    Fluid Refractory Septic Shock
    Septic Shock

NCT07273526

Laiba Qamar

1 February 2026

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