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Lumbal Erector Spinae Plane Block for Pain Management After Total Hip Arthroplasty

Lumbal Erector Spinae Plane Block for Pain Management After Total Hip Arthroplasty

Recruiting
18-85 years
All
Phase N/A

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Overview

The Erector Spinae Plane (ESP) block or spinal erector block was first described in September 2016 by a Canadian team. It's a block that was initially used for the treatment of chronic thoracic neuropathic pain. The ESP block is one of the inter-fascicular blocks and it's an easy-to-perform technique.In the literature, it has been reported that Lumbar ESPB provides effective analgesia after a hip surgery.

The purpose of this prospective randomized study was to compare the analgesic effects of the ultrasound-guided lumbar Erector Spinae Plane block on postoperative pain management versus the multimodal analgesia after total hip arthroplasty.

Description

Patients aged more than 18 years, ASA I-III scheduled for primary total hip arthroplasty with lateral approach and under general anesthesia Patients were randomly assigned, into 1 of 2 groups, namely, group ESPBL and group Placebo, using sealed envelopes

  • For ESPBL group: Lumbar ESP block performed after anesthesia induction. A low-frequency ultrasound probe will be placed longitudinally 2-3 cm lateral to the L4 transverse process. Erector spinae muscle will be visualized on the hyperechoic transverse process. The block needle (100 mm, 22G) will be inserted cranio-caudal direction and following confirmation of the correct position of the needle, between the erectorspinae muscle and the transverse process,30 ml of local anesthetic (0.25% bupivacaine/0.2% ropivacaine) will be administered for the block.
  • For Placebo group: patients had multimodal analgesia without lumbar ESP block Patients will be transferred to continuous care unit for 24 hours.

Post-operative analgesia will include:

  1. Paracetamol 1g IV every 8 hours for 1 day then oral paracetamol 1g every 8 hours for 4 weeks.
  2. Diclofenac sodium(50mg) 1 tablet x 2 per day for 5 days.
  3. PCA morphine (Patient Controlled Analgesia), as a rescue analgesia, programmed as: Bolus of 1mg/ refractory period of 10 min/ maximum dose set up at 10mg every 12h.

The primary outcome of the study is to compare postoperative opioids consumption in the first 24 postoperative hours.

Secondary endpoints:

Secondary outcomes are: intraoperative opioid consumption, postoperative pain scores, sitting position and adverse effects related to opioids.

Eligibility

Inclusion Criteria:

  • primary total hip arthroplasty with lateral approach and under general anesthesia .

Exclusion Criteria:

  • • Contraindication or refusal to regional anesthesia
    • Contraindication to non-steroidal anti-inflammatory (NSAID's)
    • Allergy to opioids
    • Allergy to paracetamol
    • Creatinine clearance \< 30ml/min
    • Weight\<50 kg or \>100kg
    • Psychiatric disorders and difficulty of communication
    • Lower limb neurological deficit
    • Patients undergoing bilateral or revision total hip replacement

Study details
    Total Hip Arthroplasty (THA)

NCT07240961

University Tunis El Manar

1 February 2026

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