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Lymphovenous Bypass Procedure for Secondary Prevention of Lymphedema in Breast Cancer

Lymphovenous Bypass Procedure for Secondary Prevention of Lymphedema in Breast Cancer

Recruiting
18 years and older
All
Phase N/A

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Overview

This study aims to evaluate the effectiveness of the Lymphovenous Bypass (LVB) procedure compared to physiotherapy alone as secondary prevention of lymphedema in breast cancer patients undergoing axillary lymph node dissection.

Description

In the intervention group, LVB was performed with intima-to-intima coaptation using the super microsurgery technique. The anastomosis was between the afferent lymphatic vessel and the recipient vein. The upper extremity lymphedema (UEL) index and indocyanine green (ICG) lymphography are utilized to evaluate the progression of lymphedema.

Eligibility

Inclusion Criteria:

  • Breast cancer patients aged ≥ 18 years with an ECOG score \> 1
  • Breast cancer patients with post-axillary lymph node dissection diagnosed with stage 0 and I lymphedema.
  • Those who have never undergone lymphedema physiotherapy.

Exclusion Criteria:

  • Patients with dermal backflow before axillary lymph node dissection (ALND).
  • Patients with breast cancer lymphedema who are unable to undergo a 24-month follow-up at Dharmais Cancer Hospital.
  • Patients with iodine allergy, severe asthma, decreased kidney function, pregnancy, or breastfeeding.

Study details
    Lymphedema Arm

NCT07233863

Dharmais National Cancer Center Hospital

1 February 2026

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