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Investigation Into the Dynamic Variations of End-Tidal Carbon Monoxide Concentration (ETCOc) in Neonates Utilizing Non-Dispersive Infrared Spectroscopy and Its Implications for Jaundice Management

Investigation Into the Dynamic Variations of End-Tidal Carbon Monoxide Concentration (ETCOc) in Neonates Utilizing Non-Dispersive Infrared Spectroscopy and Its Implications for Jaundice Management

Recruiting
28 years and younger
All
Phase N/A

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Overview

The objective of this study is to ascertain the diagnostic threshold of end-tidal carbon monoxide (ETCOc, adjusted for ambient CO levels) within the first three days postpartum, stratified by neonatal age at birth. Additionally, the study aims to evaluate the concordance of the risk range of ETCOc, as measured by non-dispersive infrared spectroscopy, with existing literature, and to assess the reliability of this technology in the management of neonatal hyperbilirubinemia.

Eligibility

Inclusion Criteria:

  1. Newborns with gestational age of ≥ 37 weeks and birth weight of ≥ 2.5 kg;
  2. Newborns delivered by either vaginal delivery or cesarean section and with hospital stay of ≥ 3 days.

Exclusion Criteria:

  1. History of second-hand smoke exposure within 24 hours
  2. Parents smoke or are exposed to second-hand smoke.

Study details
    Neonatal Hyperbilirubinemia

NCT07346976

The Fourth Affiliated Hospital of Zhejiang University School of Medicine

1 February 2026

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