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Comparing Outcomes and Complications Following Mastisol Application for Clubfoot Casting

Comparing Outcomes and Complications Following Mastisol Application for Clubfoot Casting

Recruiting
8 years and younger
All
Phase N/A

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Overview

The purpose of this study is to assess if the application of Mastisol, a liquid adhesive, improves outcomes during bilateral clubfoot casting and reduces complications and development of complex clubfoot for the duration of their casting and up to 5 years follow-up.

Description

Study Objectives include:

  • Determine if application of Mastisol is associated with improved clubfoot outcomes including length of treatment, recurrence of clubfoot, and reconstruction of clubfoot.
  • Assess if the application of Mastisol prior to cast placement is associated with reduced cast slippage and other complications such as severe skin irritation, sores, and development of complex clubfoot.

The investigators hypothesize that Mastisol application will be associated with improved outcomes by helping to maintain a well-fitting cast, which can be key to reducing complications, optimizing correction (i.e. minimizing treatment time). Proper correction can ultimately be associated with decreased incidence of clubfoot recurrence and need for reconstruction.

Participants' participation will last roughly 8-12 weeks but may be shorter or longer depending on their response to manipulation and casting. This is a standard expectation with the Ponseti method of clubfoot casting.

Eligibility

Inclusion Criteria:

  • Patients with bilateral clubfeet
  • Starting standard of care treatment with the Ponseti method between 0-8 weeks of age
    • For patients born pre-maturely their eligibility age will be based on a corrected gestational age
  • Patients for whom at least one parent/guardian is able to converse, read, and write in English

Exclusion Criteria:

  • Patients who do not have bilateral clubfoot
  • Patients who are starting treatment for clubfoot after 8 weeks of age
  • Patients whose parents/guardians are unable to converse, read, and write in English
  • Patients whose parents/guardian do not provide or are not able to provide informed consent

Study details
    Club Foot

NCT07154550

University of Wisconsin, Madison

1 February 2026

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