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Testing a Web-based Intervention for Radioactive Iodine Symptom Management to Improve Health-related Quality of Life Among Differentiated Thyroid Cancer Patients

Testing a Web-based Intervention for Radioactive Iodine Symptom Management to Improve Health-related Quality of Life Among Differentiated Thyroid Cancer Patients

Recruiting
18 years and older
All
Phase N/A

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Overview

The goal of this clinical trial is to learn if adult patients diagnosed with differentiated thyroid cancer can easily use and benefit from an online tool aimed to provide patients with educational resources and symptom management strategies to improve their quality of life after radioactive iodine (RAI) treatment. The main questions it aims to answer are:

  1. Can patients easily use and benefit from the RAI Support intervention?
  2. Does RAI Support improve health-related quality of life (overall well-being) compared to usual care?

This research will help test better digital tools to support thyroid cancer survivors in managing their health after RAI treatment.

Researchers will compare RAI Support to treatment as usual (a publicly available informational website about thyroid cancer) to see if RAI Support works to improve patients' overall well-being.

Participants will:

  1. Receive access to RAI Support or an informational website (treatment as usual) for four weeks.
  2. Use the assigned website once a week for up to four weeks.
  3. Complete two online questionnaires (an initial questionnaire and a final questionnaire after four weeks of using the assigned website) about symptoms related to RAI treatment, mood, and confidence in managing symptoms.
  4. Complete an optional 60 minute virtual interview about your experiencing using the assigned website.

Eligibility

Inclusion Criteria:

  • Age 18 or older (papillary or follicular carcinoma)
  • Diagnosed with differentiated thyroid cancer
  • Received radioactive iodine (RAI) treatment less than or equal to three years ago.
  • Mild to moderate symptoms of RAI
  • Able to provide informed consent in English
  • Access to a computer, tablet, or smartphone with internet connectivity

Exclusion Criteria:

  • A condition that precludes providing informed consent or completing study procedures (cognitive or psychiatric condition, hearing problems) as identified by the patient's physician or as assessed by a trained study team member.

Study details
    Thyroid Neoplasms

NCT06853925

Georgetown University

1 February 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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