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Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma

Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma

Recruiting
45 years and older
All
Phase N/A

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Overview

A Prospective, Multicenter, Single-Arm, Open-Label Clinical Trial

Description

To evaluate the safety and effectiveness of VisiPlate Aqueous Shunt to lower intraocular pressure (IOP) in subjects with open-angle glaucoma for whom medical and surgical treatments have failed.

Eligibility

Inclusion Criteria:

  • Open angle, pseudoexfoliative or pigmentary glaucoma
  • IOP at preoperative visit of ≥ 20mmHg and ≤ 40mmHg
  • Visual field mean deviation score of -3dB or worse
  • Area of healthy, free and mobile conjunctiva in the target quadrant
  • Shaffer angle grade ≥ 2 in the target quadrant

Exclusion Criteria:

  • Angle closure glaucoma
  • Congenital, neovascular or other secondary glaucomas
  • Previous intraocular surgery, with the exception of uncomplicated cataract surgery
  • Previous glaucoma shunt/valve in the target quadrant
  • Clinically significant inflammation or infection in the study eye within 30 days prior to the operative visit
  • History of corneal surgery, corneal opacities or corneal disease
  • Retinal or optic nerve disorders, either degenerative or evolutive, that are not associated with the existing glaucoma condition

Study details
    Open Angle Glaucoma (OAG)

NCT07220876

Avisi Technologies Inc.

1 February 2026

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