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Gut Peptides and Bone Remodeling in Children With Neuromuscular Disorders

Gut Peptides and Bone Remodeling in Children With Neuromuscular Disorders

Recruiting
10-17 years
All
Phase N/A
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Overview

Both GIP and GLP-2 reduce bone resorption (measured as CTX) in healthy adult individuals. In this study, we will investigate whether GIP and GLP-2 reduce CTX in children with spinal muscular atrophy, duchenne muscular dystrophy, or cerebral palsy.

Eligibility

Inclusion Criteria:

\- Diagnosis with Cerebral palsy (CP), Duchenne muscular dystrophy (DMD) or Spinal muscular atrophy (SMA) resulting in the need of a wheelchair

Exclusion Criteria:

  • Use of anti-resorptive medication
  • Confounding illnesses
  • Pregnancy
  • Allergy towards the components given on the test days
  • Hgb\<6.5 mmol/L

Study details
    Spinal Muscular Atrophy (SMA)
    Cerebral Palsy (CP)
    Duchenne Muscular Dystrophy (DMD)

NCT07254988

University of Copenhagen

1 February 2026

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