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A Study of LY3549492 in Chinese Participants With Type 2 Diabetes Mellitus

A Study of LY3549492 in Chinese Participants With Type 2 Diabetes Mellitus

Recruiting
18-65 years
All
Phase 1

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Overview

The main purpose of this study is to investigate LY3549492 in Chinese participants with type 2 diabetes. Participation in the study will last about 18 weeks.

Eligibility

Inclusion Criteria:

  • Are native Chinese
  • Have type 2 diabetes for at least 6 months
  • Have been treated with diet and exercise, with or without a stable dose of metformin for at least 3 months
  • Have hemoglobin A1c (HbA1c) of at least 7% and no greater than 10%
  • Have a body mass index (BMI) of at least 20 milligrams per square meter (kg/m2) and no greater than 40 kg/m2
  • Have had a stable body weight for the 3 months prior to screening
  • Women must not be of childbearing potential

Exclusion Criteria:

  • Have type 1 diabetes or have had an episode of ketoacidosis or hyperosmolar state requiring hospitalization
  • Have had an episode of severe hypoglycemia within 6 months or have a history of hypoglycemia unawareness
  • Have a clinically significant gastric emptying abnormality
  • Have or have a history of pancreatitis
  • Have signs and symptoms of liver disease, with the exception of non-alcoholic fatty liver disease
  • Have a personal or family history of multiple endocrine neoplasia syndrome type 2 or medullary thyroid carcinoma
  • Have an uncontrolled endocrine abnormality
  • Have an abnormal blood pressure or pulse rate
  • Have a 12-lead electrocardiogram (ECG) abnormality
  • Have a significant history within the past 6 months or current evidence of comorbidities capable of altering the absorption, metabolism, or elimination of drugs, or of constituting a risk when taking the study intervention, or of interfering with the interpretation of data

Study details
    Type 2 Diabetes

NCT07073170

Eli Lilly and Company

1 February 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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